TP53, a crucial tumor suppressor gene, is the most commonly mutated gene in human
cancers. Aside from losing its tumor suppressor function, mutant p53 (mutp53) often …

Ferroptosis is a new iron-dependent form of programmed cell death characterized by iron
accumulation and lipid peroxidation. In recent years, ferroptosis has garnered enormous …

The activation of ferroptosis is a new effective way to treat drug-resistant solid tumors.
Ferroptosis is an iron-mediated form of cell death caused by the accumulation of lipid …

Although the conventional activities of p53 such as cell cycle arrest, senescence, and
apoptosis are well accepted as the major checkpoints in stress responses, accumulating …

Cell death can be executed through different subroutines. Since the description of
ferroptosis as an iron-dependent form of non-apoptotic cell death in 2012, there has been …

Ferroptosis is an iron-dependent, non-apoptotic form of regulated cell death caused by lipid
peroxidation, which is controlled by integrated oxidation and antioxidant systems. The iron …

Ferroptosis, a novel form of regulated cell death induced by iron-dependent lipid
peroxidation, plays an essential role in the development and drug resistance of tumors …

Ferroptosis is a new type of oxidative regulated cell death (RCD) driven by iron-dependent
lipid peroxidation. As major sites of iron utilization and master regulators of oxidative …

Background Ferroptosis is a newly recognized type of cell death, which is different from
traditional necrosis, apoptosis or autophagic cell death. However, the position of ferroptosis …

Ferroptosis is a new type of cell death that has been recognized in recent years and is
different from apoptosis, autophagy, and necrosis. It is mainly due to cellular iron …