Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by
impairments in social communication and social interaction and the presence of repetitive …

Mechanical forces will have been omnipresent since the origin of life, and living organisms
have evolved mechanisms to sense, interpret, and respond to mechanical stimuli. The …

Atrial fibrillation (AF) is an extremely prevalent arrhythmia that presents a wide range of
therapeutic challenges. AF usually begins in a self-terminating paroxysmal form (pAF). With …

βII spectrin, the most common isoform of non-erythrocyte spectrin, is a cytoskeleton protein
present in all nucleated cells. Interestingly, βII spectrin is essential for the development of …

Cardiac arrhythmias can follow disruption of the normal cellular electrophysiological
processes underlying excitable activity and their tissue propagation as coherent wavefronts …

Variants of SARS-CoV-2 have emerged that are more transmissible than the original virus or
that exhibit some properties of immune escape, or both. The beta (B. 1.351) variant has …

Ion channels and cytoskeletal proteins in the cardiac dyad play a critical role in maintaining
excitation-contraction (EC) coupling and provide cardiac homeostasis. Functional changes …

Background—Long QT syndrome confers susceptibility to ventricular arrhythmia,
predisposing to syncope, seizures, and sudden death. While rare globally, long QT …

Tumor‐associated macrophages (TAMs) are the most abundant immune cells in the tumor
microenvironment, and the M2‐type TAMs can promote tumor growth, invasion and …

Background & Aims Loss of Spectrin beta, non-erythrocytic 1 (SPTBN1) plays an important
role in the carcinogenesis of hepatocellular carcinoma (HCC); however, the mechanisms …