The precorneal tear film is a complex mixture of proteins, lipids, metabolites, and electrolytes
with different structures and functionalities. Sustainable production of each tear component …

Over the last 2 decades, several coronaviruses (CoVs) have crossed the species barrier into
humans, causing highly prevalent and severe respiratory diseases, often with fatal …

Dysfunction of microglia is known to play an important role in Alzheimer's disease (AD).
Here, we investigated the role of RIPK1 in microglia mediating the pathogenesis of AD …

Current research efforts on neurological diseases are focused on identifying novel disease
biomarkers to aid in diagnosis, provide accurate prognostic information and monitor disease …

As an abundantly expressed cysteine protease inhibitor widely distributed in the organisms,
cystatin C is involved in various physiological processes. Due to its relatively small …

Cysteine cathepsins are lysosomal enzymes belonging to the papain family. Their
expression is misregulated in a wide variety of tumors, and ample data prove their …

Dear Editor, Human saliva is an inquisitively complex fluid and has an imperative role for
prevention and protection from viral infection, particularly through innate immune system …

Recently several reports have demonstrated that innate immune response and inflammation
have an important role in major neurodegenerative diseases. The activation of the NF-κB …

Cystatins are endogenous and reversible inhibitors of cysteine peptidases that are important
players in cancer progression. Besides their primary role as regulators of cysteine peptidase …

Alzheimer's disease (AD) represents the most frequent type of dementia in elderly people.
There are two major forms of the disease: sporadic (SAD)—whose causes are not …