Astrocytes are abundant glial cells in the central nervous system (CNS) that play active roles
in health and disease. Recent technologies have uncovered the functional heterogeneity of …

The astrocyte, a major glial cell type in the central nervous system (CNS), is widely regarded
as a functionally diverse mediator of homeostasis. During development and throughout …

Sleep is integral to cardiovascular health 1, 2. Yet, the circuits that connect cardiovascular
pathology and sleep are incompletely understood. It remains unclear whether cardiac injury …

In naive individuals, sensory neurons directly detect and respond to allergens, leading to
both the sensation of itch and the activation of local innate immune cells, which initiate the …

The neuroimmune system is a collection of immune cells, cytokines, and the glymphatic
system that plays a pivotal role in the pathogenesis and progression of Alzheimer's disease …

In neuroinflammatory diseases, systemic (blood-borne) leukocytes invade the central
nervous system (CNS) and lead to tissue damage. A causal relationship between …

Interleukin (IL)-3 has long been known for its hematopoietic properties. However, recent
evidence has expanded our understanding of IL-3 function by identifying IL-3 as a critical …

Astrocytes interact with various cell types, including neurons, vascular cells, microglia, and
peripheral immune cells. These interactions are crucial for regulating normal brain functions …

Abstract IL-3/STAT5 signaling pathway is crucial for the development and activation of
immune cells, contributing to the cellular response to infections and inflammatory stimuli …

Astrocyte‐microglia crosstalk is vital for neuronal survival and clearing aggregate
accumulation in neurodegenerative diseases. While interleukin‐3 (IL‐3) has been reported …