Background Improved access to effective antiretroviral therapy has meant that people living
with HIV (PLHIV) are surviving to older ages. However, PLHIV may be ageing differently to …

Neurological conditions associated with HIV remain major contributors to morbidity and
mortality and are increasingly recognized in the aging population on long-standing …

HIV-associated neurocognitive disorders (HANDs) persist even with virologic suppression
on combination antiretroviral therapy (cART), and the underlying pathophysiological …

Abstract Purpose of Review The purpose of this review was to examine characteristics that
may distinguish HIV-associated neurocognitive disorder (HAND) from early Alzheimer's …

With the advent of virally suppressive antiretroviral therapy (ART), life expectancy for
persons with human immunodeficiency virus (HIV) with access to ART now approaches that …

Background: Current HIV treatments are successful at suppressing plasma HIV RNA to
undetectable levels for most adherent patients. Yet, emerging evidence suggests that viral …

Objective Chronic inflammation and vascular dysfunction (eg, chronic endothelial activation)
are related yet dissociable mechanisms of HIV-associated neurocognitive impairment (NCI) …

Human immunodeficiency virus (HIV) enters the brain early after infecting humans and may
remain in the central nervous system despite successful antiretroviral treatment. Many …

Objective To test the hypothesis that brain white matter hyperintensities (WMH) are more
common in people living with HIV (PLWH), even in the setting of well-controlled infection …

Objectives: Mounting evidence indicates that vascular risk factors (VRFs) are elevated in HIV
and play a significant role in the development and persistence of HIV-associated …