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Zooming in on common immune evasion mechanisms of pathogens in phagolysosomes: potential broad-spectrum therapeutic targets against infectious diseases
The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to
propagate and cause fatal diseases. The microbes overpower host immunity at various …
propagate and cause fatal diseases. The microbes overpower host immunity at various …
Phytochemicals: Targeting autophagy to treat psoriasis
H Chen, Z Su, X Pan, X Zheng, H Li, Z Ye, B Tang, Y Lu… - Phytomedicine, 2023 - Elsevier
Background Psoriasis is an immune-mediated chronic inflammatory skin disease
characterized by well-defined erythema and white scales, which affects approximately 2% of …
characterized by well-defined erythema and white scales, which affects approximately 2% of …
The role of TLR4-mediated MyD88/TRAF6/NF-κB signaling and pIgR intestinal expression in chicks during Salmonella enteritidis infection
C Zhang, Y Ding, YF Liu, HB Wang, XJ Wang… - Veterinary Immunology …, 2023 - Elsevier
To observe the effect of Salmonella enteritidis (SE)-induced inflammation on pIgR
expression in jejunum and ileum. Salmonella enteritidis was orally administered to 7-day old …
expression in jejunum and ileum. Salmonella enteritidis was orally administered to 7-day old …
E3 Ubiquitin Ligase RNF13 Suppresses TLR Lysosomal Degradation by Promoting LAMP‐1 Proteasomal Degradation
W Liu, Y Wang, S Liu, X Zhang, X Cao… - Advanced …, 2024 - Wiley Online Library
As a highly organized system, endo‐lysosomes play a crucial role in maintaining immune
homeostasis. However, the mechanisms involved in regulating endo‐lysosome progression …
homeostasis. However, the mechanisms involved in regulating endo‐lysosome progression …
[HTML][HTML] Effects of amber LED on inflammatory and regulatory monocytes and lymphocytes
K de Brito Sousa, TC dos Santos Malavazzi… - … of Photochemistry and …, 2024 - Elsevier
The primary objective of the present study was to assess the impact of amber LED
photobiomodulation (PBM) on human monocytes and lymphocytes that were polarized into …
photobiomodulation (PBM) on human monocytes and lymphocytes that were polarized into …
[HTML][HTML] The many Achilles' heels of B and T cell tolerance
R Pelanda, J Zikherman - Immunological reviews, 2022 - ncbi.nlm.nih.gov
Generation of enormous antigen receptor repertoire diversity through random VDJ
recombination is the cornerstone of the adaptive immune system, but it comes at the cost of …
recombination is the cornerstone of the adaptive immune system, but it comes at the cost of …