Mechanisms of immunothrombosis and vasculopathy in antiphospholipid syndrome
JS Knight, Y Kanthi - Seminars in immunopathology, 2022 - Springer
Antiphospholipid syndrome (APS) is an autoimmune thrombophilia propelled by circulating
antiphospholipid antibodies that herald vascular thrombosis and obstetrical complications …
antiphospholipid antibodies that herald vascular thrombosis and obstetrical complications …
Antiphospholipid syndrome
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence
of antiphospholipid antibodies, such as lupus anticoagulant, anticardiolipin antibodies and …
of antiphospholipid antibodies, such as lupus anticoagulant, anticardiolipin antibodies and …
Release of neutrophil extracellular traps by neutrophils stimulated with antiphospholipid antibodies: a newly identified mechanism of thrombosis in the …
Objective Antiphospholipid antibodies (aPL), especially those targeting β2‐glycoprotein I
(β2GPI), are well known to activate endothelial cells, monocytes, and platelets, with …
(β2GPI), are well known to activate endothelial cells, monocytes, and platelets, with …
Diagnosing antiphospholipid syndrome:'extra-criteria'manifestations and technical advances
S Sciascia, MC Amigo, D Roccatello… - Nature Reviews …, 2017 - nature.com
First described in the early 1980s, antiphospholipid syndrome (APS) is a unique form of
acquired autoimmune thrombophilia in which patients present with clinical features of …
acquired autoimmune thrombophilia in which patients present with clinical features of …
Moonlighting chromatin: when DNA escapes nuclear control
J Singh, M Boettcher, M Dölling, A Heuer… - Cell Death & …, 2023 - nature.com
Extracellular chromatin, for example in the form of neutrophil extracellular traps (NETs), is an
important element that propels the pathological progression of a plethora of diseases. DNA …
important element that propels the pathological progression of a plethora of diseases. DNA …
In vivo role of neutrophil extracellular traps in antiphospholipid antibody–mediated venous thrombosis
Objective Antiphospholipid syndrome (APS) is a leading acquired cause of thrombotic
events. Although antiphospholipid antibodies have been shown to promote thrombosis in …
events. Although antiphospholipid antibodies have been shown to promote thrombosis in …
[HTML][HTML] The role of beta-2-glycoprotein I in health and disease associating structure with function: More than just APS
Abstract Beta-2-Glycoprotein I (β2GPI) plays a number of essential roles throughout the
body. β2GPI, C-reactive protein and thrombomodulin are the only three proteins that …
body. β2GPI, C-reactive protein and thrombomodulin are the only three proteins that …
The relevance of “non-criteria” clinical manifestations of antiphospholipid syndrome: 14th international congress on antiphospholipid antibodies technical task force …
MM Abreu, A Danowski, DG Wahl, MC Amigo… - Autoimmunity …, 2015 - Elsevier
The purpose of this task force was to critically analyze nine non-criteria manifestations of
APS to support their inclusion as APS classification criteria. The Task Force Members …
APS to support their inclusion as APS classification criteria. The Task Force Members …
Development of a new international antiphospholipid syndrome classification criteria phase I/II report: generation and reduction of candidate criteria
Objective An international multidisciplinary initiative, jointly supported by the American
College of Rheumatology and European Alliance of Associations for Rheumatology, is …
College of Rheumatology and European Alliance of Associations for Rheumatology, is …
The clinical significance of antiphospholipid antibodies in systemic lupus erythematosus
Antiphospholipid syndrome (APS) is the association of thrombosis and/or pregnancy
morbidity with antiphospholipid antibodies (aPL). Thirty to forty percent of systemic lupus …
morbidity with antiphospholipid antibodies (aPL). Thirty to forty percent of systemic lupus …