A risk-stratified approach to colorectal cancer prevention and diagnosis

MA Hull, CJ Rees, L Sharp, S Koo - Nature Reviews Gastroenterology & …, 2020 - nature.com
Population screening and endoscopic surveillance are used widely to prevent the
development of and death from colorectal cancer (CRC). However, CRC remains a major …

Biochemical markers of colorectal cancer–present and future

W Jelski, B Mroczko - Cancer management and research, 2020 - Taylor & Francis
According to a report by the National Cancer Institute, colorectal cancer (CRC) is one of the
most common types of cancer worldwide. CRC is often recognized too late for successful …

Detection of colorectal cancer in urine using DNA methylation analysis

S Bach, I Paulis, NR Sluiter, M Tibbesma, I Martin… - Scientific reports, 2021 - nature.com
Colorectal cancer (CRC) is the second leading cause for cancer-related death globally.
Clinically, there is an urgent need for non-invasive CRC detection. This study assessed the …

Next-Generation sequencing transforming clinical practice and precision medicine

D Yadav, B Patil-Takbhate, A Khandagale… - Clinica Chimica …, 2023 - Elsevier
Next-generation sequencing (NGS) has revolutionized the field of genomics and is rapidly
transforming clinical diagnosis and precision medicine. This advanced sequencing …

Plasma cell‐free DNA methylome profiling in pre‐and post‐surgery oral cavity squamous cell carcinoma

KB Patel, TA Padhya, J Huang… - Molecular …, 2023 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC), a highly heterogeneous disease that
involves multiple anatomic sites, is a leading cause of cancer‐related mortality worldwide …

Clinical implication of liquid biopsy in colorectal cancer patients treated with metastasectomy

S Lee, YS Park, WJ Chang, JY Choi, A Lim, B Kim… - Cancers, 2021 - mdpi.com
Simple Summary Circulating tumor DNA (ctDNA) is tumor-derived fragmented DNA in the
bloodstream that was shed from primary and/or metastatic tumors. ctDNA in patients with …

Liquid biopsy for early cancer detection: technological revolutions and clinical dilemma

SW Fu, C Tang, X Tan, S Srivastava - Expert Review of Molecular …, 2024 - Taylor & Francis
Introduction Liquid biopsy is an innovative advancement in oncology, offering a noninvasive
method for early cancer detection and monitoring by analyzing circulating tumor cells, DNA …

Methylated circulating tumor DNA as a biomarker for colorectal cancer diagnosis, prognosis, and prediction

FJ Nassar, ZS Msheik, RR Nasr, SN Temraz - Clinical Epigenetics, 2021 - Springer
Worldwide, colorectal cancer (CRC) is a deadly disease whose death rate ranks second
among cancers though its incidence ranks third. Early CRC detection is key and is …

Explorative cost-effectiveness analysis of colorectal cancer recurrence detection with next-generation sequencing liquid biopsy in Spain, France, and Germany

W Schramm, Y Hollenbenders… - Therapeutic Advances …, 2024 - journals.sagepub.com
Background: Next-generation sequencing liquid biopsy (NGS-LB) for colorectal cancer
(CRC) detection and surveillance remains an expensive technology as economies of scale …

Circulating tumor DNA as a preoperative marker of recurrence in patients with peritoneal metastases of colorectal cancer: a clinical feasibility study

JJ Beagan, NR Sluiter, S Bach, PP Eijk, SL Vlek… - Journal of Clinical …, 2020 - mdpi.com
Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) may
be curative for colorectal cancer patients with peritoneal metastases (PMs) but it has a high …