[HTML][HTML] Antimicrobial peptides: an emerging category of therapeutic agents
Antimicrobial peptides (AMPs), also known as host defense peptides, are short and
generally positively charged peptides found in a wide variety of life forms from …
generally positively charged peptides found in a wide variety of life forms from …
Persistent bacterial infections and persister cells
RA Fisher, B Gollan, S Helaine - Nature Reviews Microbiology, 2017 - nature.com
Many bacteria can infect and persist inside their hosts for long periods of time. This can be
due to immunosuppression of the host, immune evasion by the pathogen and/or ineffective …
due to immunosuppression of the host, immune evasion by the pathogen and/or ineffective …
Bacterial persisters: molecular mechanisms and therapeutic development
H Niu, J Gu, Y Zhang - Signal transduction and targeted therapy, 2024 - nature.com
Persisters refer to genetically drug susceptible quiescent (non-growing or slow growing)
bacteria that survive in stress environments such as antibiotic exposure, acidic and …
bacteria that survive in stress environments such as antibiotic exposure, acidic and …
Formation, physiology, ecology, evolution and clinical importance of bacterial persisters
Persisters are transiently tolerant variants that allow populations to avoid eradication by
antibiotic treatment. Their antibiotic tolerance is non-genetic, not inheritable and results from …
antibiotic treatment. Their antibiotic tolerance is non-genetic, not inheritable and results from …
Phages for biofilm removal
Biofilms are clusters of bacteria that live in association with surfaces. Their main
characteristic is that the bacteria inside the biofilms are attached to other bacterial cells and …
characteristic is that the bacteria inside the biofilms are attached to other bacterial cells and …
Bacterial heterogeneity and antibiotic survival: understanding and combatting persistence and heteroresistance
For decades, mankind has dominated the battle against bacteria, yet the tide is slowly
turning. Our antibacterial strategies are becoming less effective, allowing bacteria to get the …
turning. Our antibacterial strategies are becoming less effective, allowing bacteria to get the …
Treating bacterial infections with bacteriophage-based enzybiotics: in vitro, in vivo and clinical application
Over the past few decades, we have witnessed a surge around the world in the emergence
of antibiotic-resistant bacteria. This global health threat arose mainly due to the overuse and …
of antibiotic-resistant bacteria. This global health threat arose mainly due to the overuse and …
Fighting bacterial persistence: Current and emerging anti-persister strategies and therapeutics
In addition to the well-known strategies of antibiotic resistance and biofilm formation,
bacterial populations possess an additional survival strategy to endure hostile environments …
bacterial populations possess an additional survival strategy to endure hostile environments …
Bacteriophages as weapons against bacterial biofilms in the food industry
Microbiological contamination in the food industry is often attributed to the presence of
biofilms in processing plants. Bacterial biofilms are complex communities of bacteria …
biofilms in processing plants. Bacterial biofilms are complex communities of bacteria …
The preclinical and clinical progress of bacteriophages and their lytic enzymes: the parts are easier than the whole
The therapeutic potential of phages has been considered since their first identification more
than a century ago. The evident concept of using a natural predator to treat bacterial …
than a century ago. The evident concept of using a natural predator to treat bacterial …