Evolution of hybrid hydrogels: Next-generation biomaterials for drug delivery and tissue engineering

MM Rana, H De la Hoz Siegler - Gels, 2024 - mdpi.com
Hydrogels, being hydrophilic polymer networks capable of absorbing and retaining aqueous
fluids, hold significant promise in biomedical applications owing to their high water content …

Hyaluronic acid as a bioactive component for bone tissue regeneration: Fabrication, modification, properties, and biological functions

F **ng, C Zhou, D Hui, C Du, L Wu, L Wang… - Nanotechnology …, 2020 - degruyter.com
Hyaluronic acid (HA) is widely distributed in the human body, and it is heavily involved in
many physiological functions such as tissue hydration, wound repair, and cell migration. In …

[HTML][HTML] Growth factor–loaded sulfated microislands in granular hydrogels promote hMSCs migration and chondrogenic differentiation

A Puiggalí-Jou, M Asadikorayem, K Maniura-Weber… - Acta Biomaterialia, 2023 - Elsevier
Cell-based therapies for articular cartilage lesions are expensive and time-consuming;
clearly, a one-step procedure to induce endogenous repair would have significant clinical …

Rapid extraction and detection of biomolecules via a microneedle array of wet‐crosslinked methacrylated hyaluronic acid

SH Park, YJ Kim, S Park, H Hong… - Advanced materials …, 2022 - Wiley Online Library
The rapid detection of biomolecule levels in the human body is often required to monitor
human health. Although swellable microneedle arrays are widely used to extract …

[HTML][HTML] Applications of vibrational spectroscopy for analysis of connective tissues

W Querido, S Kandel, N Pleshko - Molecules, 2021 - mdpi.com
Advances in vibrational spectroscopy have propelled new insights into the molecular
composition and structure of biological tissues. In this review, we discuss common …

Immunomodulatory microgels support proregenerative macrophage activation and attenuate fibroblast collagen synthesis

S Mohammadi, H Ravanbakhsh… - Advanced …, 2022 - Wiley Online Library
Scars composed of fibrous connective tissues are natural consequences of injury upon
incisional wound healing in soft tissues. Hydrogels that feature a sustained presentation of …

Injectable hydrogel with immobilized BMP-2 mimetic peptide for local bone regeneration

KA Gultian, R Gandhi, K DeCesari, V Romiyo… - … in biomaterials science, 2022 - frontiersin.org
Osteoporosis is a disease characterized by a decrease in bone mineral density, thereby
increasing the risk of sustaining a fragility fracture. Most medical therapies are systemic and …

Self‐Forming Norbornene‐Tetrazine hydrogels with independently tunable properties

KA Gultian, R Gandhi, TWB Kim… - Macromolecular …, 2023 - Wiley Online Library
Although photopolymerization reactions are commonly used to form hydrogels, these
strategies rely on light and may not be suitable for delivering therapeutics in a minimally …

Hybrid networks of hyaluronic acid and poly (trimethylene carbonate) for tissue regeneration

AMC Gielen, M Ankone, DW Grijpma… - …, 2022 - ACS Publications
To improve the mechanical performance of hyaluronic acid (HA)-based hydrogels, we
prepared novel hybrid hydrogels consisting of hydrophilic HA and hydrophobic poly …

Preparing modified hyaluronic acid with tunable content of vinyl groups for use in fabrication of scaffolds by photoinduced crosslinking

AV Sochilina, AG Savelyev, RA Akasov… - Russian Journal of …, 2021 - Springer
Materials based on hyaluronic acid (HA) are extensively used in tissue engineering as
scaffolds. Photoinduced crosslinking is one way to prepare them, and, for this, HA must be …