Epigenetics and epigenomics in diabetic kidney disease and metabolic memory
M Kato, R Natarajan - Nature Reviews Nephrology, 2019 - nature.com
The development and progression of diabetic kidney disease (DKD), a highly prevalent
complication of diabetes mellitus, are influenced by both genetic and environmental factors …
complication of diabetes mellitus, are influenced by both genetic and environmental factors …
Diabetic nephropathy–complications and treatment
AKH Lim - International journal of nephrology and renovascular …, 2014 - Taylor & Francis
Diabetic nephropathy is a significant cause of chronic kidney disease and end-stage renal
failure globally. Much research has been conducted in both basic science and clinical …
failure globally. Much research has been conducted in both basic science and clinical …
Circulating microRNAs as novel biomarkers for diabetes mellitus
C Guay, R Regazzi - Nature Reviews Endocrinology, 2013 - nature.com
Diabetes mellitus is characterized by insulin secretion from pancreatic β cells that is
insufficient to maintain blood glucose homeostasis. Autoimmune destruction of β cells …
insufficient to maintain blood glucose homeostasis. Autoimmune destruction of β cells …
Biomarkers of diabetic kidney disease
HM Colhoun, ML Marcovecchio - Diabetologia, 2018 - Springer
Diabetic kidney disease (DKD) remains one of the leading causes of reduced lifespan in
diabetes. The quest for both prognostic and surrogate endpoint biomarkers for advanced …
diabetes. The quest for both prognostic and surrogate endpoint biomarkers for advanced …
MicroRNAs in kidney physiology and disease
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression.
They have important roles during kidney development, homeostasis and disease. In …
They have important roles during kidney development, homeostasis and disease. In …
Diabetic nephropathy—emerging epigenetic mechanisms
M Kato, R Natarajan - Nature Reviews Nephrology, 2014 - nature.com
Diabetic nephropathy (DN), a severe microvascular complication frequently associated with
both type 1 and type 2 diabetes mellitus, is a leading cause of renal failure. The condition …
both type 1 and type 2 diabetes mellitus, is a leading cause of renal failure. The condition …
[HTML][HTML] Large differences in small RNA composition between human biofluids
PM Godoy, NR Bhakta, AJ Barczak, H Cakmak… - Cell reports, 2018 - cell.com
Extracellular microRNAs (miRNAs) and other small RNAs are implicated in cellular
communication and may be useful as disease biomarkers. We systematically compared …
communication and may be useful as disease biomarkers. We systematically compared …
Urinary exosomal microRNAs in incipient diabetic nephropathy
F Barutta, M Tricarico, A Corbelli, L Annaratone… - PloS one, 2013 - journals.plos.org
MicroRNAs (miRNAs), a class of small non-protein-encoding RNAs, regulate gene
expression via suppression of target mRNAs. MiRNAs are present in body fluids in a …
expression via suppression of target mRNAs. MiRNAs are present in body fluids in a …
[HTML][HTML] Bovine milk exosomes contain microRNA and mRNA and are taken up by human macrophages
H Izumi, M Tsuda, Y Sato, N Kosaka, T Ochiya… - Journal of dairy …, 2015 - Elsevier
We reported previously that microRNA (miRNA) are present in whey fractions of human
breast milk, bovine milk, and rat milk. Moreover, we also confirmed that so many mRNA …
breast milk, bovine milk, and rat milk. Moreover, we also confirmed that so many mRNA …
Urinary exosomal miRNA signature in type II diabetic nephropathy patients
D Delić, C Eisele, R Schmid, P Baum, F Wiech, M Gerl… - PloS one, 2016 - journals.plos.org
MicroRNAs (miRNAs) are short non-coding RNA species which are important post-
transcriptional regulators of gene expression and play an important role in the pathogenesis …
transcriptional regulators of gene expression and play an important role in the pathogenesis …