[HTML][HTML] Decoding the Postulated Entourage Effect of Medicinal Cannabis: What It Is and What It Isn't

C Christensen, M Rose, C Cornett, M Allesø - Biomedicines, 2023 - mdpi.com
The 'entourage effect'term was originally coined in a pre-clinical study observing
endogenous bio-inactive metabolites potentiating the activity of a bioactive …

[HTML][HTML] The neurotherapeutic arsenal in Cannabis sativa: Insights into anti-neuroinflammatory and neuroprotective activity and potential entourage effects

AK Al-Khazaleh, X Zhou, DJ Bhuyan, GW Münch… - Molecules, 2024 - mdpi.com
Cannabis, renowned for its historical medicinal use, harbours various bioactive compounds—
cannabinoids, terpenes, and flavonoids. While major cannabinoids like delta-9 …

Fungal and mycotoxin contaminants in cannabis and hemp flowers: Implications for consumer health and directions for further research

KD Gwinn, MCK Leung, AB Stephens… - Frontiers in …, 2023 - frontiersin.org
Medicinal and recreational uses of Cannabis sativa, commonly known as cannabis or hemp,
has increased following its legalization in certain regions of the world. Cannabis and hemp …

Determining antioxidant activity of Cannabis leaves extracts from different varieties—Unveiling nature's treasure trove

A Stasiłowicz-Krzemień, S Sip, P Szulc… - Antioxidants, 2023 - mdpi.com
Cannabis leaves contain a diverse range of antioxidants, including cannabinoids,
flavonoids, and phenolic compounds, which offer significant health benefits. Utilising …

Antimicrobial, Probiotic, and Immunomodulatory Potential of Cannabis sativa Extract and Delivery Systems

A Stasiłowicz-Krzemień, D Szymanowska, P Szulc… - Antibiotics, 2024 - mdpi.com
The compounds present in hemp show multidirectional biological activity. It is related to the
presence of secondary metabolites, mainly cannabinoids, terpenes, and flavonoids, and the …

Antitumor Effects of Cannabis sativa Bioactive Compounds on Colorectal Carcinogenesis

R Silva-Reis, AMS Silva, PA Oliveira, SM Cardoso - Biomolecules, 2023 - mdpi.com
Cannabis sativa is a multipurpose plant that has been used in medicine for centuries.
Recently, considerable research has focused on the bioactive compounds of this plant …

Industrial hemp as a multi-purpose crop: Last achievements and research in 2018− 2023

P Dudziec, K Warmiński, MJ Stolarski - Journal of Natural Fibers, 2024 - Taylor & Francis
Industrial hemp cultivation was restricted years ago in most countries, thus wi** out
centuries of science and genetic resources. It is only since the 1990s that hemp has been …

Cannabinoids for substance use disorder treatment: what does the current evidence say?

JAB Fernandes, R Filev, TM Fidalgo - Cannabis and Cannabinoid …, 2023 - liebertpub.com
Background: The prevalence of Substance Use Disorder (SUD) is increasing along with the
need to develop approaches to reduce the harm associated with substance use, including …

[HTML][HTML] The Entourage Effect in Cannabis Medicinal Products: A Comprehensive Review

R André, AP Gomes, C Pereira-Leite… - Pharmaceuticals, 2024 - mdpi.com
This study explores the complementary or synergistic effects of medicinal cannabis
constituents, particularly terpenes, concerning their therapeutic potential, known as the …

[HTML][HTML] Comprehensive profiling of terpenes and terpenoids in different cannabis strains using GC× GC-TOFMS

J Kaur, N Sun, JE Hill - Separations, 2023 - mdpi.com
Cannabis contains a wide range of terpenes and terpenoids that are mainly responsible for
their distinctive aroma and flavor. These compounds have also demonstrated therapeutic …