Cutaneous and mucocutaneous leishmaniasis: Differential diagnosis, diagnosis, histopathology, and management

MZ Handler, PA Patel, R Kapila, Y Al-Qubati… - Journal of the American …, 2015 - Elsevier
The diagnosis of leishmaniasis can be challenging because it mimics both infectious and
malignant conditions. A misdiagnosis may lead to an unfavorable outcome. Using culture …

From infection to vaccination: reviewing the global burden, history of vaccine development, and recurring challenges in global leishmaniasis protection

G Volpedo, RH Huston, EA Holcomb… - Expert review of …, 2021 - Taylor & Francis
Introduction Leishmaniasis is a major public health problem and the second most lethal
parasitic disease in the world due to the lack of effective treatments and vaccines. Even …

Leishmania tarentolae: a vaccine platform to target dendritic cells and a surrogate pathogen for next generation vaccine research in leishmaniases and viral …

C Bandi, JA Mendoza-Roldan, D Otranto, A Alvaro… - Parasites & …, 2023 - Springer
Parasites of the genus Leishmania are unusual unicellular microorganisms in that they are
characterized by the capability to subvert in their favor the immune response of mammalian …

Vaccine candidates against leishmania under current research

S Iborra, JC Solana, JM Requena… - Expert review of …, 2018 - Taylor & Francis
Introduction: The search for vaccines to prevent human leishmaniasis is an active field of
investigation aimed to prevent the devastating effects of this family of diseases on human …

Leishmania Hijacks Myeloid Cells for Immune Escape

M Martínez-López, M Soto, S Iborra… - Frontiers in …, 2018 - frontiersin.org
Protozoan parasites of the Leishmania genus are the causative agents of leishmaniasis, a
group of neglected tropical diseases whose clinical manifestations vary depending on the …

[HTML][HTML] Advances in Leishmania Vaccines: Current Development and Future Prospects

A Ayala, A Llanes, R Lleonart, CM Restrepo - Pathogens, 2024 - mdpi.com
Leishmaniasis is a neglected tropical disease caused by parasites of the genus Leishmania.
As approved human vaccines are not available, treatment and prevention rely heavily on …

Detection of Leishmania tarentolae in lizards, sand flies and dogs in southern Italy, where Leishmania infantum is endemic: hindrances and opportunities

JA Mendoza-Roldan, MS Latrofa, R Iatta… - Parasites & …, 2021 - Springer
Background Leishmania tarentolae is a protozoan isolated from geckoes (Tarentola
annularis, Tarentola mauritanica), which is considered non-pathogenic and is transmitted by …

Contained Mycobacterium tuberculosis infection induces concomitant and heterologous protection

J Nemeth, GS Olson, AC Rothchild, AN Jahn… - PLoS …, 2020 - journals.plos.org
Progress in tuberculosis vaccine development is hampered by an incomplete understanding
of the immune mechanisms that protect against infection with Mycobacterium tuberculosis …

Role of pro-inflammatory cytokine IL-17 in Leishmania pathogenesis and in protective immunity by Leishmania vaccines

A Banerjee, P Bhattacharya, AB Joshi, N Ismail… - Cellular …, 2016 - Elsevier
The clinical outcome of Leishmania pathogenesis ranges from active skin lesions to fatal
visceral dissemination and severely impaired T cell immunity. It is well established that a …

Live attenuated Leishmania donovani centrin gene–deleted parasites induce IL-23–dependent IL-17–protective immune response against visceral leishmaniasis in a …

A Banerjee, P Bhattacharya, PK Dagur… - The Journal of …, 2018 - journals.aai.org
No vaccine exists against visceral leishmaniasis. To develop effective vaccines, we have
previously reported protective role of live attenuated centrin gene–deleted Leishmania …