Contaminant exposure in terrestrial vertebrates

PN Smith, GP Cobb, C Godard-Codding, D Hoff… - Environmental …, 2007 - Elsevier
Here we review mechanisms and factors influencing contaminant exposure among
terrestrial vertebrate wildlife. There exists a complex mixture of biotic and abiotic factors that …

Preparation and culture of precision-cut organ slices from human and animal

RL Fisher, AEM Vickers - Xenobiotica, 2013 - Taylor & Francis
1. Human and animal precision-cut organ slices are being widely used to obtain drug
metabolism and toxicity profiles in vitro. These data are then used to predict what might be …

[HTML][HTML] Assessment of polycyclic aromatic hydrocarbons (PAHs) in Mediterranean top marine predators stranded in SE Spain

G López-Berenguer, A Acosta-Dacal, OP Luzardo… - Chemosphere, 2023 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants. Although
they are not bioaccumulated in vertebrates, chronic exposures might still derive on serious …

Investigating the potential impact of polycyclic aromatic hydrocarbons (PAHs) and polychlorinated biphenyls (PCBs) on gene biomarker expression and global DNA …

P Cocci, G Mosconi, L Bracchetti, JM Nalocca… - Science of the Total …, 2018 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) and polychlorinated biphenyls (PCBs) are priority
contaminants that bioaccumulate through the food webs and affect the biology of a variety of …

[HTML][HTML] Phase-1 bioactivation mechanisms of aflatoxin through AhR, CAR and PXR nuclear receptors and the interactions with Nigella sativa seeds and …

MB Ates, M Ortatatli - Ecotoxicology and Environmental Safety, 2021 - Elsevier
Aflatoxins (AFs) are metabolised in two main phases in the liver. Cytochrome p450 enzyme
(CYP) 1A1 and CYP2A6 are expressed through AhR, CAR and PXR nuclear receptors in …

Establishment, Characterization, and Toxicological Application of Loggerhead Sea Turtle (Caretta caretta) Primary Skin Fibroblast Cell Cultures

SJ Webb, GV Zychowski, SW Bauman… - … science & technology, 2014 - ACS Publications
Pollution is a well-known threat to sea turtles but its impact is poorly understood. In vitro
toxicity testing presents a promising avenue to assess and monitor the effects of …

First assessment of POPs and cytochrome P450 expression in Cuvier's beaked whales (Ziphius cavirostris) skin biopsies from the Mediterranean Sea

M Baini, C Panti, MC Fossi, P Tepsich, B Jiménez… - Scientific Reports, 2020 - nature.com
The Cuvier's beaked whale (Ziphius cavirostris) is one of the least known cetacean species
worldwide. The decreasing population trend and associated threats has led to the IUCN …

Transcriptomic analysis of bottlenose dolphin (Tursiops truncatus) skin biopsies to assess the effects of emerging contaminants

D Lunardi, L Abelli, C Panti, L Marsili, MC Fossi… - Marine environmental …, 2016 - Elsevier
Chemicals discovered in water at levels that may be significantly different than expected are
referred to as contaminants of emerging concern (CECs) because the risk to environmental …

Pacific Ocean–wide profile of CYP1A1 expression, stable carbon and nitrogen isotope ratios, and organic contaminant burden in sperm whale skin biopsies

CAJ Godard-Codding, R Clark, MC Fossi… - Environmental …, 2011 - ehp.niehs.nih.gov
Background Ocean pollution affects marine organisms and ecosystems as well as humans.
The International Oceanographic Commission recommends ocean health monitoring …

[LIBRO][B] Wildlife toxicology: emerging contaminant and biodiversity issues

RJ Kendall, TE Lacher, GC Cobb, SB Cox - 2016 - taylorfrancis.com
Updating the extremely successful Wildlife Toxicology and Population Modeling (CRC
Press, 1994), Wildlife Toxicology: Emerging Contaminant and Biodiversity Issues brings …