Human papillomavirus as a driver of head and neck cancers

ME Sabatini, S Chiocca - British journal of cancer, 2020 - nature.com
The human papillomavirus (HPV) family includes more than 170 different types of virus that
infect stratified epithelium. High-risk HPV is well established as the primary cause of cervical …

Current perspectives on recurrent HPV-mediated oropharyngeal cancer

T Guo, SY Kang, EEW Cohen - Frontiers in Oncology, 2022 - frontiersin.org
In the recent years, the prevalence of HPV-positive oropharyngeal squamous cell carcinoma
(OPSCC) has increased significantly. Currently, nearly 80-90% of all oropharynx tumors are …

The prevalence of human papillomavirus in oropharyngeal cancer is increasing regardless of sex or race, and the influence of sex and race on survival is modified by …

F Faraji, EM Rettig, HL Tsai, M El Asmar, N Fung… - Cancer, 2019 - Wiley Online Library
Background The purpose of this study was to evaluate the influence of sex and race/ethnicity
upon prevalence trends of human papillomavirus (HPV) in oropharyngeal cancer (OPC) and …

Cell-free HPV-DNA as a biomarker for oropharyngeal squamous cell carcinoma—a step towards personalized medicine?

N Wuerdemann, R Jain, A Adams, EJM Speel… - Cancers, 2020 - mdpi.com
Simple Summary Human papillomavirus (HPV)-related oropharyngeal squamous cell
carcinoma (OPSCC) is a distinct tumor entity with relatively favorable overall survival …

Clinical uncertainties of circulating tumor DNA in human papillomavirus–related oropharyngeal squamous cell carcinoma in the absence of National Comprehensive …

DX **e, C Kut, H Quon, TY Seiwert… - Journal of Clinical …, 2022 - pmc.ncbi.nlm.nih.gov
It is well-established that human papillomavirus (HPV) is etiologically responsible for a
distinct subset of oropharyngeal squamous cell carcinomas (OPSCCs) and is an …

Oncogenic viruses and chemoresistance: What do we know?

JS Nahand, N Rabiei, R Fathazam… - Pharmacological …, 2021 - Elsevier
Chemoresistance is often referred to as a major leading reason for cancer therapy failure,
causing cancer relapse and further metastasis. As a result, an urgent need has been raised …

[HTML][HTML] Plasma cell-free human papillomavirus oncogene E6 and E7 DNA predicts outcome in oropharyngeal squamous cell carcinoma

H Reder, VF Taferner, C Wittekindt… - The Journal of Molecular …, 2020 - Elsevier
Persistent human papillomavirus (HPV) infection is associated with the development of
oropharyngeal squamous cell carcinoma (OPSCC), and increasing incidences of OPSCC …

Prognostic significance of extranodal extension in HPV-mediated oropharyngeal carcinoma: a systematic review and meta-analysis

L Benchetrit, SJ Torabi, B Givi… - … –Head and Neck …, 2021 - journals.sagepub.com
Objective To determine the prognostic role of extranodal extension (ENE) among patients
with human papilloma virus–positive (HPV+) oropharyngeal squamous cell carcinoma …

Neutrophil to lymphocyte ratio in oropharyngeal squamous cell carcinoma: A systematic review and meta-analysis

JP Rodrigo, M Sánchez-Canteli, A Triantafyllou… - Cancers, 2023 - mdpi.com
Simple Summary Neutrophil-to-lymphocyte ratio (NLR) in peripheral blood samples has
been associated with prognosis in several cancers, including head and neck cancer, but in …

The role of human papillomavirus on the prognosis and treatment of oropharyngeal carcinoma

N Fung, F Faraji, H Kang, C Fakhry - Cancer and Metastasis Reviews, 2017 - Springer
Human papillomavirus positive oropharyngeal cancer (HPV-positive OPC) is a distinct
subtype of head and neck carcinoma (HNC) distinguished from HPV-negative HNC by its …