Sensitivity to vaccines, therapeutic antibodies, and viral entry inhibitors and advances to counter the SARS-CoV-2 Omicron variant

H Zhou, M Møhlenberg, JC Thakor… - Clinical microbiology …, 2022‏ - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) keeps evolving and
mutating into newer variants over time, which gain higher transmissibility, disease severity …

Clinical severity of COVID-19 in patients admitted to hospital during the omicron wave in South Africa: a retrospective observational study

W Jassat, SSA Karim, C Mudara, R Welch… - The Lancet Global …, 2022‏ - thelancet.com
Background Up to the end of January, 2022, South Africa has had four recognisable COVID-
19 pandemic waves, each predominantly dominated by one variant of concern: the ancestral …

Analysis of anti-SARS-CoV-2 Omicron-neutralizing antibody titers in different vaccinated and unvaccinated convalescent plasma sources

DJ Sullivan, M Franchini, MJ Joyner… - Nature …, 2022‏ - nature.com
The latest SARS-CoV-2 variant of concern Omicron, with its immune escape from
therapeutic anti-Spike monoclonal antibodies and WA-1 vaccine-elicited sera, demonstrates …

Replicating RNA platform enables rapid response to the SARS-CoV-2 Omicron variant and elicits enhanced protection in naïve hamsters compared to ancestral …

DW Hawman, K Meade-White, C Clancy, J Archer… - …, 2022‏ - thelancet.com
Background In late 2021, the SARS-CoV-2 Omicron (B. 1.1. 529) variant of concern (VoC)
was reported with many mutations in the viral spike protein that were predicted to enhance …

Pathogenicity of SARS-CoV-2 Omicron (R346K) variant in Syrian hamsters and its cross-neutralization with different variants of concern

S Mohandas, PD Yadav, G Sapkal, AM Shete… - …, 2022‏ - thelancet.com
Summary Background SARS-CoV-2 Omicron variant is rampantly spreading across the
globe. We assessed the pathogenicity and immune response generated by BA. 1.1 sub …

Spike protein-independent attenuation of SARS-CoV-2 Omicron variant in laboratory mice

S Liu, P Selvaraj, K Sangare, B Luan, TT Wang - Cell Reports, 2022‏ - cell.com
Despite being more transmissible, the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) Omicron variant only causes milder diseases in laboratory animals, often …

[HTML][HTML] НОВЫЙ ШТАММ SARS-COV-2 ОМИКРОН-КЛИНИКА, ЛЕЧЕНИЕ, ПРОФИЛАКТИКА (ОБЗОР ЛИТЕРАТУРЫ)

ВИ Вечорко, ОВ Аверков, АА Зимин - … терапия и профилактика, 2022‏ - cyberleninka.ru
Несмотря на снижение уровня заболеваемости, на сегодняшний день проблема новой
коронавирусной инфекции (COVID-19, COronaVIrus Disease 2019) в глобальном …

Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model

PAC Wing, M Prange-Barczynska, A Cross… - PLoS …, 2022‏ - journals.plos.org
Understanding the host pathways that define susceptibility to Severe-acute-respiratory-
syndrome-coronavirus-2 (SARS-CoV-2) infection and disease are essential for the design of …

Booster vaccination with Ad26. COV2. S or an Omicron-adapted vaccine in pre-immune hamsters protects against Omicron BA. 2

M Swart, J Van Der Lubbe, S Schmit-Tillemans… - npj Vaccines, 2023‏ - nature.com
Since the original outbreak of the SARS-CoV-2 virus, several rapidly spreading SARS-CoV-
2 variants of concern (VOC) have emerged. Here, we show that a single dose of Ad26 …