[HTML][HTML] Mitochondrial dysfunction in type 2 diabetes mellitus: an organ-based analysis
Type 2 diabetes mellitus (T2DM) is a systemic disease characterized by hyperglycemia,
hyperlipidemia, and organismic insulin resistance. This pathological shift in both circulating …
hyperlipidemia, and organismic insulin resistance. This pathological shift in both circulating …
[HTML][HTML] Recent advances in the molecular genetics of type 2 diabetes mellitus
Type 2 diabetes mellitus (T2DM) is a complex disease in which both genetic and
environmental factors interact in determining impaired β-cell insulin secretion and peripheral …
environmental factors interact in determining impaired β-cell insulin secretion and peripheral …
Association of mitochondrial DNA levels with frailty and all-cause mortality
Mitochondrial function is altered with age and variants in mitochondrial DNA (mtDNA)
modulate risk for several age-related disease states. However, the association of mtDNA …
modulate risk for several age-related disease states. However, the association of mtDNA …
Type 2 diabetes mellitus duration and obesity alter the efficacy of autologously transplanted bone marrow-derived mesenchymal stem/stromal cells
Human bone marrow-derived mesenchymal stem/stromal cells (BM-MSCs) represent
promising stem cell therapy for the treatment of type 2 diabetes mellitus (T2DM), but the …
promising stem cell therapy for the treatment of type 2 diabetes mellitus (T2DM), but the …
The causal role of mitochondrial dynamics in regulating insulin resistance in diabetes: link through mitochondrial reactive oxygen species
Background. Mitochondrial dynamics (mtDYN) has been proposed as a bridge between
mitochondrial dysfunction and insulin resistance (IR), which is involved in the pathogenesis …
mitochondrial dysfunction and insulin resistance (IR), which is involved in the pathogenesis …
Mitochondrial reactive oxygen species and type 1 diabetes
J Chen, SE Stimpson… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: The complex etiology of type 1 diabetes (T1D) is the outcome of failures in
regulating immunity in combination with beta cell perturbations. Mitochondrial dysfunction in …
regulating immunity in combination with beta cell perturbations. Mitochondrial dysfunction in …
Metabolic syndrome and β-oxidation of long-chain fatty acids in the brain, heart, and kidney mitochondria
A Panov, VI Mayorov, S Dikalov - International Journal of Molecular …, 2022 - mdpi.com
We present evidence that metabolic syndrome (MetS) represents the postreproductive stage
of the human postembryonic ontogenesis. Accordingly, the genes governing this stage …
of the human postembryonic ontogenesis. Accordingly, the genes governing this stage …
[HTML][HTML] RAPD and ISSR based evaluation of genetic stability of micropropagated plantlets of Morus alba L. variety S-1
Plant regeneration through rapid in vitro clonal propagation of nodal explants of Morus alba
L. variety S-1 was established along with genetic stability analysis of regenerates. Axillary …
L. variety S-1 was established along with genetic stability analysis of regenerates. Axillary …
Mitochondrial DNA mutations associated with type 2 diabetes mellitus in Chinese Uyghur population
W Jiang, R Li, Y Zhang, P Wang, T Wu, J Lin, J Yu… - Scientific reports, 2017 - nature.com
A hospital-based case-control study was conducted to investigate potential association
between mitochondrial DNA and Type 2 diabetes mellitus (T2DM) in Chinese Uyghur …
between mitochondrial DNA and Type 2 diabetes mellitus (T2DM) in Chinese Uyghur …
Mitochondria in health, aging and diseases: the epigenetic perspective
The rate/quality of human aging and the development/progression of diseases depend on a
complex interplay among genetics, epigenetics and environment. In this scenario …
complex interplay among genetics, epigenetics and environment. In this scenario …