Meta‐analysis of major histocompatibility complex (MHC) class IIA reveals polymorphism and positive selection in many vertebrate species
Pathogen‐mediated selection and sexual selection are important drivers of evolution. Both
processes are known to target genes of the major histocompatibility complex (MHC), a gene …
processes are known to target genes of the major histocompatibility complex (MHC), a gene …
A 454 multiplex sequencing method for rapid and reliable genoty** of highly polymorphic genes in large-scale studies
Background High-throughput sequencing technologies offer new perspectives for
biomedical, agronomical and evolutionary research. Promising progresses now concern the …
biomedical, agronomical and evolutionary research. Promising progresses now concern the …
Major histocompatibility complex class I diversity limits the repertoire of T cell receptors
Major histocompatibility complex (MHC) genes encode proteins that initiate adaptive
immune responses through the presentation of foreign antigens to T cells. The high …
immune responses through the presentation of foreign antigens to T cells. The high …
Coevolutionary relationship between helminth diversity and MHC class II polymorphism in rodents
Parasite‐mediated selection on major histocompatibility complex (MHC) genes has mainly
been explored at the intraspecific level, although many molecular studies have revealed …
been explored at the intraspecific level, although many molecular studies have revealed …
Contrasted evolutionary histories of two Toll-like receptors (Tlr4 and Tlr7) in wild rodents (MURINAE)
Background In vertebrates, it has been repeatedly demonstrated that genes encoding
proteins involved in pathogen-recognition by adaptive immunity (eg MHC) are subject to …
proteins involved in pathogen-recognition by adaptive immunity (eg MHC) are subject to …
Long term patterns of association between MHC and helminth burdens in the bank vole support Red Queen dynamics
Major histocompatibility complex (MHC) genes encode proteins crucial for adaptive
immunity of vertebrates. Negative frequency‐dependent selection (NFDS), resulting from …
immunity of vertebrates. Negative frequency‐dependent selection (NFDS), resulting from …
Extensive MHC Class II B Gene Duplication in a Passerine, the Common Yellowthroat (Geothlypis trichas)
The major histocompatibility complex (MHC) is characterized by a birth and death model of
evolution involving gene duplication, diversification, loss of function, and deletion. As a …
evolution involving gene duplication, diversification, loss of function, and deletion. As a …
Evaluating patterns of convergent evolution and trans-species polymorphism at MHC immunogenes in two sympatric stickleback species
The immunologically important major histocompatibility complex (MHC) harbors some of the
most polymorphic genes in vertebrates. These genes presumably evolve under parasite …
most polymorphic genes in vertebrates. These genes presumably evolve under parasite …
Association between the DQA MHC class II gene and Puumala virus infection in Myodes glareolus, the bank vole
Puumala virus (PUUV) is a hantavirus specifically harboured by the bank vole, Myodes
(earlier Clethrionomys) glareolus. It causes a mild form of hemorrhagic fever with renal …
(earlier Clethrionomys) glareolus. It causes a mild form of hemorrhagic fever with renal …
Gene duplication, allelic diversity, selection processes and adaptive value of MHC class II DRB genes of the bank vole, Clethrionomys glareolus
The generation and maintenance of allelic polymorphism in genes of the major
histocompatibility complex (MHC) is a central issue in evolutionary genetics. Recently, the …
histocompatibility complex (MHC) is a central issue in evolutionary genetics. Recently, the …