Recent advances in microbial production of L-malic acid

N Wu, J Zhang, Y Chen, Q Xu, P Song, Y Li… - Applied Microbiology …, 2022 - Springer
Over the last few decades, increasing concerns regarding fossil fuel depletion and
excessive CO2 emissions have led to extensive fundamental studies and industrial trials …

Microbial biosynthesis of L-malic acid and related metabolic engineering strategies: advances and prospects

Z Wei, Y Xu, Q Xu, W Cao, H Huang… - Frontiers in Bioengineering …, 2021 - frontiersin.org
Malic acid, a four-carbon dicarboxylic acid, is widely used in the food, chemical and medical
industries. As an intermediate of the TCA cycle, malic acid is one of the most promising …

[HTML][HTML] Microbial L-malic acid production: history, current progress, and perspectives

Y **, F Fan, X Zhang - Green Carbon, 2023 - Elsevier
Abstract L-malic acid (L-MA) is an important intermediate in the tricarboxylic acid cycle and a
crucial bulk chemical with various applications in the food, pharmaceutical, and chemical …

Recent advances in microbial production of malic acid from renewable byproducts

J Iyyappan, G Baskar, E Gnansounou… - … Science and Bio …, 2019 - Springer
In the last few years, ecofriendly malic acid production has received a potential platform for
the bio-based chemicals to replace the dependency of fossil based resources. The main …

Effects of volatile fatty acids on soil properties, microbial communities, and volatile metabolites in wheat rhizosphere of loess

W Chen, P He, H Zhang, F Lü - Journal of Cleaner Production, 2024 - Elsevier
Abstract The Loess Plateau faces critical challenges due to soil degradation. In this context,
using volatile fatty acids (VFAs) from biowaste as readily available soil conditioners offer …

Valorization of Crude Glycerol into Citric Acid and Malic Acid by Yarrowia lipolytica

X Qian, N Xu, Y **g, M Song, J Zhou… - Industrial & …, 2020 - ACS Publications
Glycerol is a byproduct generated in large amounts during the process of biodiesel
production. The present study reports an alternative method of crude glycerol valorization for …

Microbial production of L-malate from renewable non-food feedstocks

Y Jiang, X Ye, T Zheng, W Dong, F **n, J Ma… - Chinese Journal of …, 2021 - Elsevier
L-malate is an intermediate of the tricarboxylic acid cycle which is naturally occurred in
various microorganisms, and it has been widely applied in polymer, beverage and food …

[PDF][PDF] Recent advances in producing food additive L‐malate: Chassis, substrate, pathway, fermentation regulation and application

Q Ding, C Ye - Microbial Biotechnology, 2023 - Wiley Online Library
In addition to being an important intermediate in the TCA cycle, L‐malate is also widely used
in the chemical and beverage industries. Due to the resulting high demand, numerous …

Progress on production of malic acid and succinic acid by industrially-important engineered microorganisms

N Wu, W Wang, J Zhu - Journal of Biotechnology, 2025 - Elsevier
Organic acids are widely used as additives in the food, pharmaceutical, chemical, and
plastic industries. Currently, the industrial production methods of organic acids mainly …

High Yield Fermentation of L-serine in Recombinant Escherichia coli via Co-localization of SerB and EamA through Protein Scaffold

KNT Tran, A Kumaravel, J Jeong, SH Hong - … and Bioprocess Engineering, 2022 - Springer
L-serine is a non-essential amino acid which has a wide range of applications and plays an
important role as a building block for growing cells. L-serine microbial development is …