Significant advances in the management of cystic fibrosis (CF) in recent decades have
dramatically changed the epidemiology and prognosis of this serious disease, which is no …

Since the first description of cystic fibrosis in 1938, there have been significant advances in
both quality of life and longevity for people living with this disease. In this article we describe …

Newborn screening (NBS) for cystic fibrosis (CF) is increasingly being implemented and is
soon likely to be in use throughout the United States, because early detection permits …

ContextAlthough Pseudomonas aeruginosa is the most common virulent respiratory
pathogen in cystic fibrosis (CF), the longitudinal development of P aeruginosa infection and …

The survival of patients with cystic fibrosis (CF) continues to improve. The discovery and
cloning of the CFTR gene more than 21 years ago led to the identification of the structure …

Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator
(CFTR) gene which encodes a protein expressed in the apical membrane of exocrine …

Objective. Despite its relative frequency among autosomal recessive diseases and the
availability of the sweat test, cystic fibrosis (CF) has been difficult to diagnose in early …

Rationale: Better understanding of evolution of lung function in infants with cystic fibrosis
(CF) and its association with pulmonary inflammation and infection is crucial in informing …

Since the late 1970s when the potential of the immunoreactive trypsinogen assay for early
identification of infants with cystic fibrosis was first recognised, the performance of newborn …

Objective To determine the relation of growth and nutritional status to pulmonary function in
young children with cystic fibrosis (CF). Study design The relation of weight-for-age (WFA) …