While machine learning (ML) has made significant contributions to the biopharmaceutical
field, its applications are still in the early stages in terms of providing direct support for quality …

Continuous bioprocessing is significantly changing the biological drugs (or biologics)
manufacturing landscape by potentially improving product quality, process stability, and …

The biopharmaceutical industries are continuously faced with the pressure to reduce the
development costs and accelerate development time scales. The traditional approach of …

The biopharmaceutical market has experienced a tremendous growth in the last years.
However, this growth should be balanced considering the difficulty in bioproduct …

As the biopharmaceutical industry advances to meet the pressures of an expanding product
portfolio and global demand, it will continue to face new challenges while concurrently …

Protein A chromatography is an enabling technology in current manufacturing processes of
monoclonal antibodies (mAbs) and mAb derivatives, largely due to its ability to reduce the …

The capabilities of digital twins (DT) and the successes they have demonstrated in various
industries have attracted significant attention from the biopharmaceutical manufacturing …

Protein A capture chromatography, which forms the core of the mAb purification platform,
demands cautious use and maximum resin utilization due to high cost associated with resin …

BACKGROUND Monoclonal antibodies (mAbs) presently dominate the biotherapeutic
market. However, biotherapeutics in general, and mAbs in particular, are expensive …

Therapeutic monoclonal antibodies (mAbs) provide new means for treatments of a wide
range of diseases and comprise a large fraction of all new approved drugs. Production of …