[HTML][HTML] Chronic stress impacts the cardiovascular system: animal models and clinical outcomes
Psychological stresses are associated with cardiovascular diseases to the extent that
cardiovascular diseases are among the most important group of psychosomatic diseases …
cardiovascular diseases are among the most important group of psychosomatic diseases …
The renin-angiotensin system: a target of and contributor to dyslipidemias, altered glucose homeostasis, and hypertension of the metabolic syndrome
K Putnam, R Shoemaker… - American Journal of …, 2012 - journals.physiology.org
The renin-angiotensin system (RAS) is an important therapeutic target in the treatment of
hypertension. Obesity has emerged as a primary contributor to essential hypertension in the …
hypertension. Obesity has emerged as a primary contributor to essential hypertension in the …
Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: potential implications for inflammation and plaque instability
Background—Patients with an activated renin-angiotensin system (RAS) or genetic
alterations of the RAS are at increased risk of myocardial infarction (MI). Administration of …
alterations of the RAS are at increased risk of myocardial infarction (MI). Administration of …
Upregulation of endothelial receptor for oxidized low-density lipoprotein (LOX-1) in cultured human coronary artery endothelial cells by angiotensin II type 1 receptor …
Cross talk between oxidized LDL (ox-LDL) and angiotensin II (Ang II) may be relevant in
atherosclerosis. In this study, we examined the presence of a specific endothelial receptor …
atherosclerosis. In this study, we examined the presence of a specific endothelial receptor …
NADPH oxidases in the vasculature: molecular features, roles in disease and pharmacological inhibition
Until the 1970s, reactive oxygen species (ROS) were considered merely harmful by-
products of aerobic respiration and the driving force behind the evolution of an array of …
products of aerobic respiration and the driving force behind the evolution of an array of …
Current and emerging drug targets in heart failure treatment
After initial strategies targeting inotropism and congestion, the neurohormonal interpretative
model of heart failure (HF) pathophysiology has set the basis for current pharmacological …
model of heart failure (HF) pathophysiology has set the basis for current pharmacological …
Angiotensin II-induced superoxide anion generation in human vascular endothelial cells: role of membrane-bound NADH-/NADPH-oxidases
H Zhang, A Schmeißer, CD Garlichs… - Cardiovascular …, 1999 - academic.oup.com
Abstract Background: Angiotensin II (ANG II) mediated hypertension accelerates
atherosclerosis (AS) and thereby increases the incidence of myocardial infarction (MI). On …
atherosclerosis (AS) and thereby increases the incidence of myocardial infarction (MI). On …
Oxidized LDL upregulates angiotensin II type 1 receptor expression in cultured human coronary artery endothelial cells: the potential role of transcription factor NF-κB
Background—We demonstrated earlier that angiotensin II (Ang II), by AT1 receptor
activation, upregulates oxidized LDL (ox-LDL) endothelial receptor LOX-1 gene expression …
activation, upregulates oxidized LDL (ox-LDL) endothelial receptor LOX-1 gene expression …
Upregulation of renin-angiotensin system during differentiation of monocytes to macrophages
A Okamura, H Rakugi, M Ohishi… - Journal of …, 1999 - journals.lww.com
Background We have demonstrated that accumulated macrophages in human coronary
arteries strongly express angiotensin converting enzyme in accordance with the …
arteries strongly express angiotensin converting enzyme in accordance with the …
The multiple actions of angiotensin II in atherosclerosis
Angiotensin II (Ang II), the effector peptide of the renin–angiotensin system, has been
implied in the pathogenesis of atherosclerosis on various levels. There is abundant …
implied in the pathogenesis of atherosclerosis on various levels. There is abundant …