Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 38-amino acid C-terminally
α-amidated peptide that was first isolated 20 years ago from an ovine hypothalamic extract …
α-amidated peptide that was first isolated 20 years ago from an ovine hypothalamic extract …
PACAP and migraine headache: immunomodulation of neural circuits in autonomic ganglia and brain parenchyma
JA Waschek, SM Baca, S Akerman - The journal of headache and pain, 2018 - Springer
The discovery that intravenous (IV) infusions of the neuropeptide PACAP-38 (pituitary
adenylyl cyclase activating peptide-38) induced delayed migraine-like headaches in a large …
adenylyl cyclase activating peptide-38) induced delayed migraine-like headaches in a large …
Pituitary adenylate cyclase-activating polypeptide plays a key role in nitroglycerol-induced trigeminovascular activation in mice
Pituitary adenylate cyclase-activating polypeptide (PACAP) and its receptors (PAC1, VPAC)
are present in sensory neurons and vascular smooth muscle. PACAP infusion was found to …
are present in sensory neurons and vascular smooth muscle. PACAP infusion was found to …
PACAP is an endogenous protective factor—insights from PACAP-deficient mice
D Reglodi, P Kiss, K Szabadfi, T Atlasz… - Journal of Molecular …, 2012 - Springer
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a widespread neuropeptide
with a diverse array of biological functions. Not surprisingly, the lack of endogenous PACAP …
with a diverse array of biological functions. Not surprisingly, the lack of endogenous PACAP …
Targeting the PAC1 receptor for neurological and metabolic disorders
The pituitary adenylate cyclase-activating polypeptide (PACAP)-selective PAC1 receptor
(PAC1R, ADCYAP1R1) is a member of the vasoactive intestinal peptide (VIP)/secretin …
(PAC1R, ADCYAP1R1) is a member of the vasoactive intestinal peptide (VIP)/secretin …
Probiotics (Bacillus clausii and Lactobacillus fermentum NMCC-14) Ameliorate Stress Behavior in Mice by Increasing Monoamine Levels and mRNA Expression of Dopamine Receptors …
Stress is a physiological consequence of the body to adversity. The gut–brain axis and
probiotics are gaining interest to provide better treatment for stress and other neurological …
probiotics are gaining interest to provide better treatment for stress and other neurological …
[HTML][HTML] Pituitary adenylate cyclase-activating polypeptide: 30 years in research spotlight and 600 million years in service
V Denes, P Geck, A Mester, R Gabriel - Journal of clinical medicine, 2019 - mdpi.com
Emerging from the depths of evolution, pituitary adenylate cyclase-activating polypeptide
(PACAP) and its receptors (ie, PAC1, VPAC1, VPAC2) are present in multicellular organisms …
(PACAP) and its receptors (ie, PAC1, VPAC1, VPAC2) are present in multicellular organisms …
PACAP deficiency as a model of aging
Dysregulation of neuropeptides may play an important role in aging-induced impairments. In
the long list of neuropeptides, pituitary adenylate cyclase–activating polypeptide (PACAP) …
the long list of neuropeptides, pituitary adenylate cyclase–activating polypeptide (PACAP) …
Protective effects of pituitary adenylate cyclase-activating polypeptide (PACAP) against apoptosis
T Seaborn, O Masmoudi-Kouli… - Current …, 2011 - benthamdirect.com
Apoptosis is a regulated process leading to cell death, which is implicated both in normal
development and in various pathologies including heart failure, stroke and …
development and in various pathologies including heart failure, stroke and …
Inhibitory effect of PACAP on caspase activity in neuronal apoptosis: a better understanding towards therapeutic applications in neurodegenerative diseases
Programmed cell death, which is part of the normal development of the central nervous
system, is also implicated in various neurodegenerative disorders. Cysteine-dependent …
system, is also implicated in various neurodegenerative disorders. Cysteine-dependent …