Are physicochemical properties sha** the allergenic potency of animal allergens?

J Costa, C Villa, K Verhoeckx… - Clinical Reviews in …, 2022‏ - Springer
Key determinants for the development of an allergic response to an otherwise 'harmless'
food protein involve different factors like the predisposition of the individual, the timing, the …

Antimicrobial activity of mesenchymal stem cells: current status and new perspectives of antimicrobial peptide-based therapies

F Alcayaga-Miranda, J Cuenca, M Khoury - Frontiers in immunology, 2017‏ - frontiersin.org
While mesenchymal stem cells (MSCs)-based therapy appears to be promising, there are
concerns regarding possible side effects related to the unwanted suppression of …

Cow's milk protein β-lactoglobulin confers resilience against allergy by targeting complexed iron into immune cells

F Roth-Walter, SM Afify, LF Pacios, BR Blokhuis… - Journal of Allergy and …, 2021‏ - Elsevier
Background Beta-lactoglobulin (BLG) is a bovine lipocalin in milk with an innate defense
function. The circumstances under which BLG is associated with tolerance of or allergy to …

Natural killer T cells in allergic asthma: implications for the development of novel immunotherapeutical strategies

C Gutiérrez-Vera, R García-Betancourt… - Frontiers in …, 2024‏ - frontiersin.org
Allergic asthma has emerged as a prevalent allergic disease worldwide, affecting most
prominently both young individuals and lower-income populations in develo** and …

Iron-deficiency in atopic diseases: innate immune priming by allergens and siderophores

F Roth-Walter - Frontiers in Allergy, 2022‏ - frontiersin.org
Although iron is one of the most abundant elements on earth, about a third of the world's
population are affected by iron deficiency. Main drivers of iron deficiency are beside the …

Host antimicrobial peptides: the promise of new treatment strategies against tuberculosis

J Arranz-Trullén, L Lu, D Pulido, S Bhakta… - Frontiers in …, 2017‏ - frontiersin.org
Tuberculosis (TB) continues to be a devastating infectious disease and remerges as a
global health emergency due to an alarming rise of antimicrobial resistance to its treatment …

[HTML][HTML] Allergic diseases and asthma in pregnancy, a secondary publication

I Pali-Schöll, J Namazy, E Jensen-Jarolim - World Allergy Organization …, 2017‏ - Elsevier
Every fifth pregnant woman is affected by allergies, especially rhinitis and asthma. Allergic
symptoms existing before pregnancy may be either attenuated, or equally often promoted …

[HTML][HTML] Sex-dependent effects of intestinal microbiome manipulation in a mouse model of Alzheimer's disease

H Kaur, S Nookala, S Singh, S Mukundan… - Cells, 2021‏ - mdpi.com
Mechanisms linking intestinal bacteria and neurodegenerative diseases such as
Alzheimer's disease (AD) are still unclear. We hypothesized that intestinal dysbiosis might …

AllergoOncology: opposite outcomes of immune tolerance in allergy and cancer

E Jensen‐Jarolim, HJ Bax, R Bianchini, S Crescioli… - Allergy, 2018‏ - Wiley Online Library
While desired for the cure of allergy, regulatory immune cell subsets and nonclassical Th2‐
biased inflammatory mediators in the tumour microenvironment can contribute to immune …

Retinoic acid prevents immunogenicity of milk lipocalin Bos d 5 through binding to its immunodominant T-cell epitope

K Hufnagl, D Ghosh, S Wagner, A Fiocchi, L Dahdah… - Scientific reports, 2018‏ - nature.com
The major cow's milk allergen Bos d 5 belongs to the lipocalin protein family, with an
intramolecular pocket for hydrophobic ligands. We investigated whether Bos d 5 when …