[HTML][HTML] Mechanisms involved in the therapeutic properties of mesenchymal stem cells

L da Silva Meirelles, AM Fontes, DT Covas… - Cytokine & growth factor …, 2009 - Elsevier
Mesenchymal stem cells (MSCs) have been described as being able to give rise to several
quite different mesenchymal cell phenotypes. However, the ability to differentiate is not the …

Mesenchymal stem cells: environmentally responsive therapeutics for regenerative medicine

MB Murphy, K Moncivais, AI Caplan - Experimental & molecular …, 2013 - nature.com
Mesenchymal stem cells (MSCs) are partially defined by their ability to differentiate into
tissues including bone, cartilage and adipose in vitro, but it is their trophic, paracrine and …

The MSC: an injury drugstore

AI Caplan, D Correa - Cell stem cell, 2011 - cell.com
Now that mesenchymal stem cells (MSCs) have been shown to be perivascular in vivo, the
existing traditional view that focuses on the multipotent differentiation capacity of these cells …

Mesenchymal stem versus stromal cells: International Society for Cell & Gene Therapy (ISCT®) Mesenchymal Stromal Cell committee position statement on …

S Viswanathan, Y Shi, J Galipeau, M Krampera… - Cytotherapy, 2019 - Elsevier
Abstract The International Society for Cell & Gene Therapy (ISCT®) Mesenchymal Stromal
Cell (ISCT MSC) committee offers a position statement to clarify the nomenclature of …

Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in …

Q Zhang, S Shi, Y Liu, J Uyanne, Y Shi… - The Journal of …, 2009 - journals.aai.org
Aside from the well-established self-renewal and multipotent differentiation properties,
mesenchymal stem cells exhibit both immunomodulatory and anti-inflammatory roles in …

Paracrine mechanisms of mesenchymal stem cells in tissue repair

M Gnecchi, P Danieli, G Malpasso… - Mesenchymal Stem Cells …, 2016 - Springer
Tissue regeneration from transplanted mesenchymal stromal cells (MSC) either through
transdifferentiation or cell fusion was originally proposed as the principal mechanism …

Human hepatocyte transplantation for liver disease: current status and future perspectives

V Iansante, RR Mitry, C Filippi, E Fitzpatrick… - Pediatric …, 2018 - nature.com
Liver transplantation is the accepted treatment for patients with acute liver failure and liver-
based metabolic disorders. However, donor organ shortage and lifelong need for …

Stem cell conditioned medium improves acute lung injury in mice: in vivo evidence for stem cell paracrine action

L Ionescu, RN Byrne, T van Haaften… - … of Physiology-Lung …, 2012 - journals.physiology.org
Mortality and morbidity of acute lung injury and acute respiratory distress syndrome remain
high because of the lack of pharmacological therapies to prevent injury or promote repair …

Immunosuppressive properties of mesenchymal stem cells

M Abumaree, M Al Jumah, RA Pace… - Stem Cell Reviews and …, 2012 - Springer
Mesenchymal stem cells (MSC) can be isolated from different adult tissues including bone
marrow, adipose tissue, cord blood and placenta. MSCs modulate the immune function of …

Interaction of neural stem cells (NSCs) and mesenchymal stem cells (MSCs) as a promising approach in brain study and nerve regeneration

A Kaminska, K Radoszkiewicz, P Rybkowska… - Cells, 2022 - mdpi.com
Rapid developments in stem cell research in recent years have provided a solid foundation
for their use in medicine. Over the last few years, hundreds of clinical trials have been …