Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles

G Bordanaba-Florit, F Royo, SG Kruglik… - Nature …, 2021 - nature.com
Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …

Label-free microfluidic cell sorting and detection for rapid blood analysis

N Lu, HM Tay, C Petchakup, L He, L Gong, KK Maw… - Lab on a Chip, 2023 - pubs.rsc.org
Blood tests are considered as standard clinical procedures to screen for markers of diseases
and health conditions. However, the complex cellular background (> 99.9% RBCs) and …

Roadmap for optical tweezers

G Volpe, OM Maragò… - Journal of Physics …, 2023 - iopscience.iop.org
Optical tweezers are tools made of light that enable contactless pushing, trap**, and
manipulation of objects, ranging from atoms to space light sails. Since the pioneering work …

High-throughput screening technology in industrial biotechnology

W Zeng, L Guo, S Xu, J Chen, J Zhou - Trends in biotechnology, 2020 - cell.com
Based on the development of automatic devices and rapid assay methods, various high-
throughput screening (HTS) strategies have been established for improving the performance …

Raman spectroscopy and imaging in bioanalytics

D Cialla-May, C Krafft, P Rösch… - Analytical …, 2021 - ACS Publications
Since the discovery of the inelastic scattering of light, ie, the so-called Raman effect, 1
Raman spectroscopy has become an attractive tool in a high number of research fields …

[HTML][HTML] Trends in pharmaceutical analysis and quality control by modern Raman spectroscopic techniques

A Silge, K Weber, D Cialla-May… - TrAC Trends in …, 2022 - Elsevier
The application of Raman spectroscopic methods in life science applications has entered a
new era due to advances in instrumentation, miniaturization and, most importantly …

Identifying surface-enhanced raman spectra with a raman library using machine learning

Y Ju, O Neumann, M Bajomo, Y Zhao, P Nordlander… - ACS …, 2023 - ACS Publications
Since its discovery, surface-enhanced Raman spectroscopy (SERS) has shown outstanding
promise of identifying trace amounts of unknown molecules in rapid, portable formats …

Optical photothermal infrared spectroscopy with simultaneously acquired Raman spectroscopy for two-dimensional microplastic identification

JS Böke, J Popp, C Krafft - Scientific Reports, 2022 - nature.com
In recent years, vibrational spectroscopic techniques based on Fourier transform infrared
(FTIR) or Raman microspectroscopy have been suggested to fulfill the unmet need for …

Detection and differentiation of bacterial and fungal infection of neutrophils from peripheral blood using Raman spectroscopy

N Arend, A Pittner, A Ramoji, AS Mondol… - Analytical …, 2020 - ACS Publications
Neutrophils are important cells of the innate immune system and the major leukocyte
subpopulation in blood. They are responsible for recognizing and neutralizing invading …

Living sample viability measurement methods from traditional assays to nanomotion

H Al-Madani, H Du, J Yao, H Peng, C Yao, B Jiang… - Biosensors, 2022 - mdpi.com
Living sample viability measurement is an extremely common process in medical,
pharmaceutical, and biological fields, especially drug pharmacology and toxicology …