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Post-translational modifications: regulators of neurodegenerative proteinopathies
One of the hallmark features in the neurodegenerative disorders (NDDs) is the accumulation
of aggregated and/or non-functional protein in the cellular milieu. Post-translational …
of aggregated and/or non-functional protein in the cellular milieu. Post-translational …
Therapeutic implications of phosphorylation-and dephosphorylation-dependent factors of cAMP-response element-binding protein (CREB) in neurodegeneration
Neurodegeneration is a condition of the central nervous system (CNS) characterized by loss
of neural structures and function. The most common neurodegenerative disorders (NDDs) …
of neural structures and function. The most common neurodegenerative disorders (NDDs) …
Neuroprotective potency of mangiferin against 3-nitropropionic acid induced Huntington's disease-like symptoms in rats: possible antioxidant and anti-inflammatory …
Huntington's disease (HD), a neurodegenerative disease, normally starts in the prime of
adult life, followed by a gradual occurrence of psychiatric disturbances, cognitive and motor …
adult life, followed by a gradual occurrence of psychiatric disturbances, cognitive and motor …
[HTML][HTML] Neuroprotective effect of α-mangostin in ameliorating propionic acid-induced experimental model of autism in Wistar rats
Several studies have documented the role of hyper-activation of extracellular signal-
regulated kinases (ERK) in Autism pathogenesis. Alpha-mangostin (AMG) is a …
regulated kinases (ERK) in Autism pathogenesis. Alpha-mangostin (AMG) is a …
Protective effect of natural products against Huntington's disease: An overview of scientific evidence and understanding their mechanism of action
Huntington's disease (HD), a neurodegenerative disease, normally starts in the prime of
adult life, followed by a gradual occurrence of characteristic psychiatric disturbances and …
adult life, followed by a gradual occurrence of characteristic psychiatric disturbances and …
Protective effects of apigenin on methylmercury-induced behavioral/neurochemical abnormalities and neurotoxicity in rats
Methylmercury (MeHg) is a neurotoxin that induces neurotoxicity and cell death in neurons.
MeHg increases oligodendrocyte death, glial cell activation, and motor neuron …
MeHg increases oligodendrocyte death, glial cell activation, and motor neuron …
[HTML][HTML] Nrf2/HO-1 signaling stimulation through acetyl-11-keto-beta-boswellic acid (AKBA) provides neuroprotection in ethidium bromide-induced experimental …
Multiple sclerosis (MS) is a severe immune-mediated neurological disease characterized by
neuroinflammation, demyelination, and axonal degeneration in the central nervous system …
neuroinflammation, demyelination, and axonal degeneration in the central nervous system …
Guggulsterone ameliorates ethidium bromide-induced experimental model of multiple sclerosis via restoration of behavioral, molecular, neurochemical and …
Multiple Sclerosis (MS) is a progressive neurodegenerative disease with clinical signs of
neuroinflammation and the central nervous system's demyelination. Numerous studies have …
neuroinflammation and the central nervous system's demyelination. Numerous studies have …
[HTML][HTML] Guggulsterone mediated JAK/STAT and PPAR-gamma modulation prevents neurobehavioral and neurochemical abnormalities in propionic acid-induced …
Autism spectrum disorder is a neurodevelopmental disorder marked by repetitive behaviour,
challenges in verbal and non-verbal communication, poor socio-emotional health, and …
challenges in verbal and non-verbal communication, poor socio-emotional health, and …
Smo-Shh signaling activator purmorphamine ameliorates neurobehavioral, molecular, and morphological alterations in an intracerebroventricular propionic acid …
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disease characterized
by cognitive and sensorimotor impairment. Numerous research findings have consistently …
by cognitive and sensorimotor impairment. Numerous research findings have consistently …