Phenotypically identical cells can dramatically vary with respect to behavior during their
lifespan and this variation is reflected in their molecular composition such as the …

Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and
archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …

Effective clearance of an infection requires that the immune system rapidly detects and
neutralizes invading parasites while strictly avoiding self-antigens that would result in …

Bacteria adapt to environmental stimuli by adjusting their transcriptomes in a complex
manner, the full potential of which has yet to be established for any individual bacterial …

Recent advances in high-throughput RNA sequencing (RNA-seq) have enabled
tremendous leaps forward in our understanding of bacterial transcriptomes. However …

CRISPR-Cas is an RNA-mediated adaptive immune system that defends bacteria and
archaea against mobile genetic elements. Short mature CRISPR RNAs (crRNAs) are key …

Circular RNA forms had been described in all domains of life. Such RNAs were shown to
have diverse biological functions, including roles in the life cycle of viral and viroid genomes …

The human body is constantly exposed to microorganisms, which entails manifold
interactions between human cells and diverse commensal or pathogenic bacteria. The …

The prokaryotic clusters of regularly interspaced palindromic repeats (CRISPR) system
utilizes genomically encoded CRISPR RNA (crRNA), derived from invading viruses and …

RNA-seq technologies have provided significant insight into the transcription networks of
mycobacteria. However, such studies provide no definitive information on the translational …