The endosymbiotic origin, diversification and fate of plastids

PJ Keeling - … Transactions of the Royal Society B …, 2010 - royalsocietypublishing.org
Plastids and mitochondria each arose from a single endosymbiotic event and share many
similarities in how they were reduced and integrated with their host. However, the …

Metabolic maps and functions of the Plasmodium falciparum apicoplast

SA Ralph, GG Van Dooren, RF Waller… - Nature Reviews …, 2004 - nature.com
Discovery of a relict chloroplast (the apicoplast) in malarial parasites presented new
opportunities for drug development. The apicoplast–although no longer photosynthetic–is …

The Genome of the Diatom Thalassiosira Pseudonana: Ecology, Evolution, and Metabolism

EV Armbrust, JA Berges, C Bowler, BR Green… - Science, 2004 - science.org
Diatoms are unicellular algae with plastids acquired by secondary endosymbiosis. They are
responsible for∼ 20% of global carbon fixation. We report the 34 million–base pair draft …

PlasmoDB: a functional genomic database for malaria parasites

C Aurrecoechea, J Brestelli, BP Brunk… - Nucleic acids …, 2009 - academic.oup.com
Abstract PlasmoDB (http://PlasmoDB. org) is a functional genomic database for Plasmodium
spp. that provides a resource for data analysis and visualization in a gene-by-gene or …

The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum

Z Bozdech, M Llinás, BL Pulliam, ED Wong, J Zhu… - PLoS …, 2003 - journals.plos.org
Plasmodium falciparum is the causative agent of the most burdensome form of human
malaria, affecting 200–300 million individuals per year worldwide. The recently sequenced …

Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum

E Yeh, JL DeRisi - PLoS biology, 2011 - journals.plos.org
Plasmodium spp parasites harbor an unusual plastid organelle called the apicoplast. Due to
its prokaryotic origin and essential function, the apicoplast is a key target for development of …

Complete Genome Sequence of the Apicomplexan, Cryptosporidium parvum

MS Abrahamsen, TJ Templeton, S Enomoto… - Science, 2004 - science.org
The apicomplexan Cryptosporidium parvum is an intestinal parasite that affects healthy
humans and animals, and causes an unrelenting infection in immunocompromised …

Malaria parasite development in the mosquito and infection of the mammalian host

ASI Aly, AM Vaughan, SHI Kappe - Annual review of …, 2009 - annualreviews.org
Plasmodium sporozoites are the product of a complex developmental process in the
mosquito vector and are destined to infect the mammalian liver. Attention has been drawn to …

The evolution, metabolism and functions of the apicoplast

L Lim, GI McFadden - … of the Royal Society B: Biological …, 2010 - royalsocietypublishing.org
The malaria parasite, Plasmodium falciparum, harbours a relict plastid known as the
'apicoplast'. The discovery of the apicoplast ushered in an exciting new prospect for drug …

Toxoplasma gondii: the model apicomplexan

K Kim, LM Weiss - International journal for parasitology, 2004 - Elsevier
Toxoplasma gondii is an obligate intracellular protozoan parasite which is a significant
human and veterinary pathogen. Other members of the phylum Apicomplexa are also …