Clinical development and potential of photothermal and photodynamic therapies for cancer

X Li, JF Lovell, J Yoon, X Chen - Nature reviews Clinical oncology, 2020 - nature.com
Light-activated, photosensitizer-based therapies have been established as safe modalities
of tumour ablation for numerous cancer indications. Two main approaches are available …

Layered double hydroxide-based nanomaterials for biomedical applications

T Hu, Z Gu, GR Williams, M Strimaite, J Zha… - Chemical Society …, 2022 - pubs.rsc.org
Against the backdrop of increased public health awareness, inorganic nanomaterials have
been widely explored as promising nanoagents for various kinds of biomedical applications …

Design of superior phototheranostic agents guided by Jablonski diagrams

G Feng, GQ Zhang, D Ding - Chemical Society Reviews, 2020 - pubs.rsc.org
Phototheranostics represents a promising direction for modern precision medicine, which
has recently attracted great research interest from multidisciplinary research areas. Organic …

Innovative strategies for hypoxic‐tumor photodynamic therapy

X Li, N Kwon, T Guo, Z Liu… - Angewandte Chemie …, 2018 - Wiley Online Library
Despite its clinical promise, photodynamic therapy (PDT) suffers from a key drawback
associated with its oxygen‐dependent nature, which limits its effective use against hypoxic …

Supramolecular photosensitizers rejuvenate photodynamic therapy

X Li, S Lee, J Yoon - Chemical Society Reviews, 2018 - pubs.rsc.org
Owing to its spatiotemporal selectivity and noninvasive nature, photodynamic therapy (PDT)
has become a clinically promising approach for the treatment of a wide range of cancers and …

Organelle-targeted photosensitizers for precision photodynamic therapy

R Wang, X Li, J Yoon - ACS Applied Materials & Interfaces, 2021 - ACS Publications
Subcellular organelles are the cornerstones of cells, and destroying them will cause cell
dysfunction and even death. Therefore, realizing precise organelle targeting of …

[HTML][HTML] Combined photodynamic and photothermal therapy and immunotherapy for cancer treatment: a review

C Kong, X Chen - International journal of nanomedicine, 2022 - ncbi.nlm.nih.gov
Photoactivation therapy based on photodynamic therapy (PDT) and photothermal therapy
(PTT) has been identified as a tumour ablation modality for numerous cancer indications …

[HTML][HTML] Recent advances in photosensitizers as multifunctional theranostic agents for imaging-guided photodynamic therapy of cancer

P Sarbadhikary, BP George, H Abrahamse - Theranostics, 2021 - ncbi.nlm.nih.gov
In recent years tremendous effort has been invested in the field of cancer diagnosis and
treatment with an overall goal of improving cancer management, therapeutic outcome …

Ultra‐Small Nano‐Assemblies as Tumor‐Targeted and Renal Clearable Theranostic Agent for Photodynamic Therapy

D Zhang, KX Teng, L Zhao, LY Niu… - Advanced …, 2023 - Wiley Online Library
It is a challenge to design photosensitizers to balance between the tumor‐targeting
enrichment for precise treatment and efficient clearance within a reasonable timescale for …

Phthalocyanines as medicinal photosensitizers: Developments in the last five years

X Li, BD Zheng, XH Peng, SZ Li, JW Ying… - Coordination Chemistry …, 2019 - Elsevier
Owing to their high extinction coefficients, long absorption wavelengths, and modification
tunable photophysical and photochemical properties, phthalocyanines (Pcs) have been …