Complexity metrics for IMRT and VMAT plans: a review of current literature and applications

S Chiavassa, I Bessieres, M Edouard… - The British journal of …, 2019‏ - academic.oup.com
Modulated radiotherapy with multileaf collimators is widely used to improve target conformity
and normal tissue sparing. This introduced an additional degree of complexity, studied by …

[HTML][HTML] Adaptive radiotherapy enabled by MRI guidance

A Hunt, VN Hansen, U Oelfke, S Nill, S Hafeez - Clinical Oncology, 2018‏ - Elsevier
Adaptive radiotherapy (ART) strategies systematically monitor variations in target and
neighbouring structures to inform treatment-plan modification during radiotherapy. This is …

Total marrow and total lymphoid irradiation in bone marrow transplantation for acute leukaemia

JYC Wong, AR Filippi, M Scorsetti, S Hui… - The Lancet …, 2020‏ - thelancet.com
The use of total body irradiation as part of conditioning regimens for acute leukaemia is
progressively declining because of concerns of late toxic effects and the introduction of …

Multi-criteria optimization and decision-making in radiotherapy

S Breedveld, D Craft, R Van Haveren… - European Journal of …, 2019‏ - Elsevier
Radiotherapy (radiation therapy) is one of the main treatments for cancer. The aim is to
deliver a prescribed radiation dose to the tumor, while kee** the unavoidable dose to the …

[HTML][HTML] An online adaptive plan library approach for intensity modulated proton therapy for head and neck cancer

M Oud, S Breedveld, M Giżyńska, M Kroesen… - Radiotherapy and …, 2022‏ - Elsevier
Background and purpose In intensity modulated proton therapy (IMPT), the impact of setup
errors and anatomical changes is commonly mitigated by robust optimization with …

Attention‐aware 3D U‐Net convolutional neural network for knowledge‐based planning 3D dose distribution prediction of head‐and‐neck cancer

AFI Osman, NM Tamam - Journal of applied clinical medical …, 2022‏ - Wiley Online Library
Purpose Deep learning–based knowledge‐based planning (KBP) methods have been
introduced for radiotherapy dose distribution prediction to reduce the planning time and …

A fast and robust constraint-based online re-optimization approach for automated online adaptive intensity modulated proton therapy in head and neck cancer

M Oud, S Breedveld, J Rojo-Santiago… - Physics in Medicine …, 2024‏ - iopscience.iop.org
Objective. In head-and-neck cancer intensity modulated proton therapy, adaptive
radiotherapy is currently restricted to offline re-planning, mitigating the effect of slow …

Plan quality in radiotherapy treatment planning–Review of the factors and challenges

CR Hansen, M Hussein, U Bernchou… - Journal of Medical …, 2022‏ - Wiley Online Library
A high‐quality treatment plan aims to best achieve the clinical prescription, balancing high
target dose to maximise tumour control against sufficiently low organ‐at‐risk dose for …

[HTML][HTML] Automated planning for prostate stereotactic body radiation therapy on the 1.5 T MR-Linac

S Naccarato, M Rigo, R Pellegrini, P Voet… - Advances in radiation …, 2022‏ - Elsevier
Purpose Adaptive stereotactic body radiation therapy (SBRT) for prostate cancer (PC) by the
1.5 T MR-linac currently requires online planning by an expert user. A fully automated and …

Artificial intelligence in radiotherapy: a technological review

K Sheng - Frontiers of Medicine, 2020‏ - Springer
Radiation therapy (RT) is widely used to treat cancer. Technological advances in RT have
occurred in the past 30 years. These advances, such as three-dimensional image guidance …