Diabetes mellitus is defined as a group of metabolic diseases that are associated with the
presence of a hyperglycemic state due to impairments in insulin release and/or function …

Physical exercise is firmly incorporated in the management of type 1 diabetes (T1DM), due
to multiple recognized beneficial health effects (cardiovascular disease prevention being …

Effects of type 1 diabetes mellitus on skeletal muscle: clinical observations and physiological
mechanisms Page 1 Pediatric Diabetes 2011: 12: 345–364 doi: 10.1111/j.1399-5448.2010.00699.x …

The plasminogen system is a critical proteolytic system responsible for the remodeling of the
extracellular matrix (ECM). The master regulator of the plasminogen system, plasminogen …

It has been well established that bone fragility is one of the chronic complications of diabetes
mellitus, and both type 1 and type 2 diabetes are risk factors for fragility fractures. Diabetes …

Purpose.: To investigate ocular blood flow and visual function in the Ins2 Akita diabetic
retinopathy mouse model at early and late time points after onset of hyperglycemia …

Abstract Kinesin-1 and Growth Associated Protein 43 (GAP-43) localization in muscle fiber
are crucial for proper skeletal muscle hypertrophy. To evaluate this assumption, we …

Background The effects of diet-induced obesity on skeletal muscle function are largely
unknown, particularly as it relates to changes in oxidative metabolism and morphology …

Type 1 diabetes, if poorly controlled, leads to skeletal muscle atrophy, decreasing the quality
of life. We aimed to search highly responsive genes in diabetic muscle atrophy in a common …

Obesity and aging reduce skeletal muscle contractile function. However, it remains unclear
whether obesity additively promotes muscle contractile dysfunction in the setting of aging. In …