Antibiotic resistance in Pakistan: a systematic review of past decade

H Bilal, MN Khan, T Rehman, MF Hameed… - BMC infectious …, 2021 - Springer
Background During the last six decades, extensive use of antibiotics has selected resistant
strains, increasing the rate of fatal infectious diseases, and exerting an economic burden on …

Klebsiella Pneumoniae: An Update on Antibiotic Resistance Mechanisms

M Karami-Zarandi, HA Rahdar, H Esmaeili… - Future …, 2023 - Taylor & Francis
Klebsiella pneumoniae colonizes mucosal surfaces of healthy humans and is responsible
for one third of all Gram-negative infections in hospitalized patients. K. pneumoniae is …

[HTML][HTML] A systematic review and meta-analysis of carbapenem resistance and its possible treatment options with focus on clinical Enterobacteriaceae: thirty years of …

M Umair, TR Walsh, M Mohsin - Heliyon, 2024 - cell.com
Background Carbapenem resistance is epidemic worldwide, these last resort antimicrobials
are listed in the WHO 'watch group'with higher resistance potential. During the years 2017 …

Cefoperazone/sulbactam: New composites against multiresistant gram negative bacteria?

YH Ku, WL Yu - Infection, Genetics and Evolution, 2021 - Elsevier
Sulbactam, a class A β-lactamase inhibitor, added to cefoperazone either at a fixed 8 mg/L
level of sulbactam or at a level of fixed cefoperazone: sulbactam ratio (2: 1) would constitute …

Emergence of plasmid-mediated mcr genes from Gram-negative bacteria at the human-animal interface

H Javed, S Saleem, A Zafar, A Ghafoor, AB Shahzad… - Gut Pathogens, 2020 - Springer
Background The global emergence of plasmid-mediated colistin resistance (Col-R)
conferred by mcr genes in gram-negative rods (GNRs) has jeopardized the last treatment …

[HTML][HTML] Analysis of diverse β-lactamases presenting high-level resistance in association with OmpK35 and OmpK36 porins in ESBL-producing Klebsiella …

H Ejaz - Saudi journal of biological sciences, 2022 - Elsevier
Emerging extensively drug-resistant (XDR) Klebsiella pneumoniae due to the production of
β-lactamases and porin loss is a substantial worldwide concern. This study aimed to …

[HTML][HTML] Detection of Klebsiella pneumoniae antibiotic-resistant genes: an impending source of multidrug resistance dissemination through raw food

K Junaid, H Ejaz, S Younas, A Alanazi… - Saudi Journal of …, 2022 - Elsevier
This study aimed to find out the prevalence and antimicrobial resistance profile of Klebsiella
pneumoniae in raw food items. A total of 261 raw food items, including vegetables, fruits …

Discovery of Antimicrobial Agents Based on Structural and Functional Study of the Klebsiella pneumoniae MazEF Toxin–Antitoxin System

C **, SM Kang, DH Kim, Y Lee, BJ Lee - Antibiotics, 2024 - mdpi.com
Klebsiella pneumoniae causes severe human diseases, but its resistance to current
antibiotics is increasing. Therefore, new antibiotics to eradicate K. pneumoniae are urgently …

Plasmid-mediated AmpC β-Lactamase gene analysis in Klebsiella pneumoniae clinical isolates

N Jomehzadeh, K Ahmadi… - Biomedical and …, 2022 - journals.lww.com
Background: In Gram-negative bacteria, including Klebsiellapneumoniae, the production of
AmpC beta-lactamase enzymes is one of the main resistance mechanisms for beta-lactam …