Single-molecule localization microscopy
Single-molecule localization microscopy (SMLM) describes a family of powerful imaging
techniques that dramatically improve spatial resolution over standard, diffraction-limited …
techniques that dramatically improve spatial resolution over standard, diffraction-limited …
DNA origami
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …
Super-resolution microscopy demystified
Super-resolution microscopy (SRM) bypasses the diffraction limit, a physical barrier that
restricts the optical resolution to roughly 250 nm and was previously thought to be …
restricts the optical resolution to roughly 250 nm and was previously thought to be …
Ångström-resolution fluorescence microscopy
Fluorescence microscopy, with its molecular specificity, is one of the major characterization
methods used in the life sciences to understand complex biological systems. Super …
methods used in the life sciences to understand complex biological systems. Super …
Ultra‐high sensitivity mass spectrometry quantifies single‐cell proteome changes upon perturbation
Single‐cell technologies are revolutionizing biology but are today mainly limited to imaging
and deep sequencing. However, proteins are the main drivers of cellular function and in …
and deep sequencing. However, proteins are the main drivers of cellular function and in …
The biological applications of DNA nanomaterials: current challenges and future directions
W Ma, Y Zhan, Y Zhang, C Mao, X **e… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …
biological applications as driven by DNA nanotechnology in the past decades, including …
Emerging approaches to DNA data storage: challenges and prospects
With the total amount of worldwide data skyrocketing, the global data storage demand is
predicted to grow to 1.75× 1014 GB by 2025. Traditional storage methods have difficulties …
predicted to grow to 1.75× 1014 GB by 2025. Traditional storage methods have difficulties …
Super-resolution microscopy for structural cell biology
Super-resolution microscopy techniques, and specifically single-molecule localization
microscopy (SMLM), are approaching nanometer resolution inside cells and thus have great …
microscopy (SMLM), are approaching nanometer resolution inside cells and thus have great …
Deep learning massively accelerates super-resolution localization microscopy
The speed of super-resolution microscopy methods based on single-molecule localization,
for example, PALM and STORM, is limited by the need to record many thousands of frames …
for example, PALM and STORM, is limited by the need to record many thousands of frames …
The nucleolus functions as a phase-separated protein quality control compartment
INTRODUCTION Cells have evolved quality control mechanisms that operate under normal
growth conditions and during stress to maintain protein homeostasis (proteostasis) and …
growth conditions and during stress to maintain protein homeostasis (proteostasis) and …