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Therapeutic perspectives of the black cumin component thymoquinone: A review
The dietary phytochemical thymoquinone (TQ), belonging to the family of quinones, mainly
obtained from the black and angular seeds of Nigella sativa, is one of the promising …
obtained from the black and angular seeds of Nigella sativa, is one of the promising …
Synthesis of 2-methyl-5-methoxy-1, 4-benzoquinone and In-silico Activity Profiling Toward Cytochrome P450-3A4
Abstract The synthesis of 2-methyl-5-methoxy-1, 4-benzoquinone (2) was carried out by
reflux of 2-methyl-1, 4-benzoquinone (1) with MeOH and ZnCl 2 for 12 hours at ambient. The …
reflux of 2-methyl-1, 4-benzoquinone (1) with MeOH and ZnCl 2 for 12 hours at ambient. The …
Synthesis of 3-(7-triphenylphosphonioheptyl)-2, 6-dimethyl-1, 4-benzoquinone) and The Activity Test Toward Glycogen Phosphorylase Enzyme: In silico Approach
Abstract The synthesis of 3-(7-triphenylphosphonioheptyl)-2, 6-dimethyl-1, 4-
benzoquinone)(TFH) is carried out by bromoalkylation and insertion of …
benzoquinone)(TFH) is carried out by bromoalkylation and insertion of …
Novel bromoalkyl-1, 4-benzoquinones as anti-inflammatory candidate toward COX signaling: Synthesis, octanol-water solubility, and in-silico drug-target profiling
The main structure of novel bromoalkyl-1, 4-benzoquinones is quinoid ring that can be
modified to increase the bioavailability as a drug candidate. In this research, the …
modified to increase the bioavailability as a drug candidate. In this research, the …
Facile synthesis of 5-Isopropyl-2, 3-dimethylbenzene-1, 4-diol by Friedel-Crafts and Determination of Partition Coefficient in n-Octanol/Water
The wide therapeutic effect of quinone-based drugs has received considerable interest for a
long time. In this research, Friedel-Crafts performed a facile synthesis of quinone derivatives …
long time. In this research, Friedel-Crafts performed a facile synthesis of quinone derivatives …
Effect of methyl substituent on the solubility of 1, 4-benzoquinone derivatives in n-octanol/water system
The solubility of the compound is a crucial task for new drug design. Quinone is a promising
candidate to develop as a new drug. In this research, the synthesis of 1, 4-benzoquinone …
candidate to develop as a new drug. In this research, the synthesis of 1, 4-benzoquinone …
Biological Activity and Solubility of 5-Methoxy-1, 4-Benzoquinone Having Bromoheptyl and Bromodecyl Substituents in the n-Octanol/Water System
The biological activity and solubility of compounds are influenced by its chemical structure.
These properties can be improved by substituting alkyl, alkoxy, and/or haloalkane in the …
These properties can be improved by substituting alkyl, alkoxy, and/or haloalkane in the …