Hyaluronic acid biomaterials for central nervous system regenerative medicine

G Jensen, JL Holloway, SE Stabenfeldt - Cells, 2020 - mdpi.com
Hyaluronic acid (HA) is a primary component of the brain extracellular matrix and functions
through cellular receptors to regulate cell behavior within the central nervous system (CNS) …

Synthetic peptide hydrogels as 3D scaffolds for tissue engineering

X Ding, H Zhao, Y Li, AL Lee, Z Li, M Fu, C Li… - Advanced Drug Delivery …, 2020 - Elsevier
The regeneration of tissues and organs poses an immense challenge due to the extreme
complexity in the research work involved. Despite the tissue engineering approach being …

Design of recombinant spider silk proteins for cell type specific binding

VT Trossmann, T Scheibel - Advanced Healthcare Materials, 2023 - Wiley Online Library
Cytophilic (cell‐adhesive) materials are very important for tissue engineering and
regenerative medicine. However, for engineering hierarchically organized tissue structures …

[HTML][HTML] Bidirectional cell-matrix interaction dictates neuronal network formation in a brain-mimetic 3D scaffold

S Samanta, L Ylä-Outinen, VK Rangasami, S Narkilahti… - Acta Biomaterialia, 2022 - Elsevier
Human pluripotent stem cells (hPSC) derived neurons are emerging as a powerful tool for
studying neurobiology, disease pathology, and modeling. Due to the lack of platforms …

[HTML][HTML] Laminin-derived peptide, IKVAV, modulates macrophage phenotype through integrin mediation

A Jha, E Moore - Matrix Biology Plus, 2024 - Elsevier
Macrophages are highly plastic immune cells known to exist on a spectrum of phenotypes
including pro-inflammatory (M1) or pro-healing (M2). Macrophages interact with extracellular …

Neuritogenic glycosaminoglycan hydrogels promote functional recovery after severe traumatic brain injury

N Gonsalves, MK Sun, P Chopra… - Journal of Neural …, 2024 - iopscience.iop.org
Objective. Severe traumatic brain injury (sTBI) induced neuronal loss and brain atrophy
contribute significantly to long-term disabilities. Brain extracellular matrix (ECM) associated …

Combination of IKVAV, LRE, and GPQGIWGQ bioactive signaling peptides increases human induced pluripotent stem cell derived neural stem cells extracellular …

TH Perera, X Lu, SM Howell, YE Kurosu… - Advanced …, 2020 - Wiley Online Library
Extracellular matrix (ECM) remodeling is emerging as a modulator of neural maturation and
axon extension. Most studies have used rodent cells to develop matrices capable of …

Extracellular matrix of the nervous system

S Nazir, AH Feresten, L Lin, H Hutter… - Handbook of Neural …, 2025 - Elsevier
Decades of research in traditional model organisms have revealed that extracellular matrix
(ECM) within the nervous system provides not only a structural scaffold for tissue …

The promoter effect of laminin-derived IKVAV peptide on three dimensional HUVEC microtissue

ZBY Çevik, B Köken, O Karaman - … Advanced Researches and …, 2023 - dergipark.org.tr
Tissue engineering research is recently a popular field but the vascularization process of
existing methods limits the study area. Human Umbilical Vein Endothelial Cells (HUVEC) …

The response of human induced pluripotent stem cells to cyclic temperature changes explored by BIO-AFM

Y Nie, W Wang, X Xu, N Ma, A Lendlein - MRS Advances, 2021 - Springer
Human induced pluripotent stem cells (hiPSCs) are highly sensitive to extrinsic physical and
biochemical signals from their extracellular microenvironments. In this study, we analyzed …