Targeting aging and age-related diseases with vaccines

R Wu, F Sun, W Zhang, J Ren, GH Liu - Nature Aging, 2024 - nature.com
Aging is a major risk factor for numerous chronic diseases. Vaccination offers a promising
strategy to combat these age-related diseases by targeting specific antigens and inducing …

Mechanistic Approach to Immunity and Immunotherapy of Alzheimer's Disease: A Review

MR Islam, MA Rabbi, T Hossain… - ACS Chemical …, 2024 - ACS Publications
Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by
progressive cognitive decline and memory loss, affecting millions of people worldwide …

Evolving therapeutic interventions for the management and treatment of Alzheimer's disease

F Ahmad, A Karan, R Sharma, NS Sharma… - Ageing research …, 2024 - Elsevier
Alzheimer's Disease (AD) patients experience diverse symptoms, including memory loss,
cognitive impairment, behavioral abnormalities, mood changes, and mental issues. The …

[HTML][HTML] Current therapeutics for Alzheimer's disease and clinical trials

D **ao, C Zhang - Exploration of Neuroscience, 2024 - explorationpub.com
Alzheimer's disease (AD) is a major type of dementia and neurodegenerative disease,
characterized by memory loss and cognitive decline. Over decades, significant efforts have …

[HTML][HTML] Active Immunotherapy for the Prevention of Alzheimer's and Parkinson's Disease

MM Vroom, JC Dodart - Vaccines, 2024 - mdpi.com
Neurodegenerative diseases (ND) give rise to significant declines in motor, autonomic,
behavioral, and cognitive functions. Of these conditions, Alzheimer's disease (AD) and …

[HTML][HTML] Natural serine proteases and their applications in combating amyloid formation

SK Metkar, S Udayakumar, A Girigoswami… - ADMET and …, 2024 - hrcak.srce.hr
Background and purpose: Amyloidosis is a group of diseases including diabetes type II and
neurological disorders, such as Alzheimer's disease, Parkinson's disease, prion disease …

A multi-targeting immunotherapy ameliorates multiple facets of Alzheimer's disease in 3xTg mice

X Feng, Y Hou, J Liu, F Yan, M Dai, M Chen, J Wang… - npj Vaccines, 2024 - nature.com
Alzheimer's disease (AD) is an intricate disorder involving amyloid deposits, neurofibrillary
tangles, and chronic neuroinflammation. Though current Aβ-directed immunotherapies …

Potential therapeutic targets for trauma management

Z Li, O Qiao, Y Wang, N Li, Y Gong - Trends in Pharmacological Sciences, 2023 - cell.com
Despite advances in medical treatments for severe trauma, it remains a critical condition
associated with high mortality. During trauma, the release of endogenous damage …

Newer Therapeutic Approaches in Treating Alzheimer's Disease: A Comprehensive Review

R Reddi Sree, M Kalyan, N Anand, S Mani… - ACS …, 2025 - ACS Publications
Alzheimer's disease (AD) is an aging-related irreversible neurodegenerative disease
affecting mostly the elderly population. The main pathological features of AD are the …

Potential therapeutic natural compounds for the treatment of Alzheimer's disease

Q Huang, W Wu, Y Wen, S Lu, C Zhao - Phytomedicine, 2024 - Elsevier
Background Alzheimer's disease (AD) is a complicated neurodegenerative disease with
cognitive impairment occurring in the older people, in which extracellular accumulation of β …