There is a real consensus that new antibiotics are urgently needed and are the best chance
for combating antibiotic resistance. The phylum Actinobacteria is one of the main producers …

Covering: January to December 2017 This review covers the literature published in 2017 for
marine natural products (MNPs), with 740 citations (723 for the period January to December …

Streptomyces are a large and valuable resource of bioactive and complex secondary
metabolites, many of which have important clinical applications. With the advances in high …

The growing resistance of microorganisms towards antibiotics has become a serious global
problem. Therapeutics with novel chemical scaffolds and/or mechanisms of action are …

The current review aims to summarise the biodiversity and biosynthesis of novel secondary
metabolites compounds, of the phylum Actinobacteria and the diverse range of secondary …

The marine environment is a rich source of chemically diverse, biologically active natural
products, and serves as an invaluable resource in the ongoing search for novel …

Nitrogen heterocycles are essential parts of the chemical machinery of life and often reveal
intriguing structures. They are not only widespread in terrestrial habitats but can also …

Background Heterologous expression of secondary metabolite gene clusters is used to
achieve increased production of desired compounds, activate cryptic gene clusters …

One of the major challenges of agriculture currently is to obtain higher crop yield.
Environmental conditions, cultivar quality, and plant diseases greatly affect plant …

Highlights•Microorganisms are a prolific source of highly bioactive compounds.•Omics
approaches to unveil biosynthetic gene clusters encoding new natural product.•Use multi …