Marine natural products

AR Carroll, BR Copp, RA Davis, RA Keyzers… - Natural product …, 2019 - pubs.rsc.org
Covering: January to December 2017 This review covers the literature published in 2017 for
marine natural products (MNPs), with 740 citations (723 for the period January to December …

Streptomyces: Still the Biggest Producer of New Natural Secondary Metabolites, a Current Perspective

L Donald, A Pipite, R Subramani, J Owen… - Microbiology …, 2022 - mdpi.com
There is a real consensus that new antibiotics are urgently needed and are the best chance
for combating antibiotic resistance. The phylum Actinobacteria is one of the main producers …

[HTML][HTML] Mini review: Genome mining approaches for the identification of secondary metabolite biosynthetic gene clusters in Streptomyces

N Lee, S Hwang, J Kim, S Cho, B Palsson… - Computational and …, 2020 - Elsevier
Streptomyces are a large and valuable resource of bioactive and complex secondary
metabolites, many of which have important clinical applications. With the advances in high …

Secondary metabolites of actinomycetes and their antibacterial, antifungal and antiviral properties

K Jakubiec-Krzesniak, A Rajnisz-Mateusiak… - Polish journal of …, 2018 - sciendo.com
The growing resistance of microorganisms towards antibiotics has become a serious global
problem. Therapeutics with novel chemical scaffolds and/or mechanisms of action are …

Biodiversity of secondary metabolites compounds isolated from phylum actinobacteria and its therapeutic applications

MM Al-Shaibani, RMS Radin Mohamed, NM Sidik… - Molecules, 2021 - mdpi.com
The current review aims to summarise the biodiversity and biosynthesis of novel secondary
metabolites compounds, of the phylum Actinobacteria and the diverse range of secondary …

Marine pyrrole alkaloids

K Seipp, L Geske, T Opatz - Marine Drugs, 2021 - mdpi.com
Nitrogen heterocycles are essential parts of the chemical machinery of life and often reveal
intriguing structures. They are not only widespread in terrestrial habitats but can also …

Engineering of Streptomyces lividans for heterologous expression of secondary metabolite gene clusters

Y Ahmed, Y Rebets, MR Estévez, J Zapp… - Microbial cell …, 2020 - Springer
Background Heterologous expression of secondary metabolite gene clusters is used to
achieve increased production of desired compounds, activate cryptic gene clusters …

Current status and future prospects of marine natural products (MNPs) as antimicrobials

A Choudhary, LM Naughton, I Montánchez… - Marine drugs, 2017 - mdpi.com
The marine environment is a rich source of chemically diverse, biologically active natural
products, and serves as an invaluable resource in the ongoing search for novel …

A look into a multifunctional toolbox: endophytic Bacillus species provide broad and underexploited benefits for plants

R Lopes, S Tsui, PJRO Gonçalves… - World Journal of …, 2018 - Springer
One of the major challenges of agriculture currently is to obtain higher crop yield.
Environmental conditions, cultivar quality, and plant diseases greatly affect plant …

A critical review of machine-learning for “multi-omics” marine metabolite datasets

J Manochkumar, AK Cherukuri, RS Kumar… - Computers in Biology …, 2023 - Elsevier
During the last decade, genomic, transcriptomic, proteomic, metabolomic, and other omics
datasets have been generated for a wide range of marine organisms, and even more are …