Schizophrenia is routinely referred to as a neurodevelopmental disorder, but the role of
brain development in a disorder typically diagnosed during early adult life is enigmatic. The …

The three-dimensional organization of the genome plays a central role in the regulation of
cellular functions, particularly in the human brain. This review explores the intricacies of …

Neuropsychiatric and neurodegenerative diseases have a significant genetic component.
Risk variants often affect the noncoding genome, altering cis-regulatory elements (CREs) …

Our understanding of the sex-specific role of the non-coding genome in serious mental
illness remains largely incomplete. To address this gap, we explored sex differences in …

Genetic studies of schizophrenia reveal a complex polygenic risk architecture comprised of
hundreds of risk variants; most are common in the population at-large, non-coding, and act …