[HTML][HTML] Preventive therapy for latent tuberculosis infection—the promise and the challenges

GJ Fox, CC Dobler, BJ Marais, JT Denholm - International Journal of …, 2017 - Elsevier
Around one third of the world's population may harbour latent tuberculosis infection (LTBI),
an asymptomatic immunological state that confers a heightened risk of subsequently …

Progression from latent infection to active disease in dynamic tuberculosis transmission models: a systematic review of the validity of modelling assumptions

NA Menzies, E Wolf, D Connors… - The Lancet Infectious …, 2018 - thelancet.com
Mathematical modelling is commonly used to evaluate infectious disease control policy and
is influential in sha** policy and budgets. Mathematical models necessarily make …

Nutritional supplementation to prevent tuberculosis incidence in household contacts of patients with pulmonary tuberculosis in India (RATIONS): a field-based, open …

A Bhargava, M Bhargava, A Meher, A Benedetti… - The Lancet, 2023 - thelancet.com
Summary Background In India, tuberculosis and undernutrition are syndemics with a high
burden of tuberculosis coexisting with a high burden of undernutrition in patients and in the …

Clinical standards for the diagnosis, treatment and prevention of TB infection

GB Migliori, SJ Wu, A Matteelli, D Zenner… - … of Tuberculosis and …, 2022 - ingentaconnect.com
BACKGROUND: Tuberculosis (TB) preventive therapy (TPT) decreases the risk of
develo** TB disease and its associated morbidity and mortality. The aim of these clinical …

[HTML][HTML] First characterization of the CD4 and CD8 T-cell responses to QuantiFERON-TB Plus

E Petruccioli, T Chiacchio, I Pepponi, V Vanini, R Urso… - Journal of Infection, 2016 - Elsevier
Summary Introduction QuantiFERON®-TB Gold Plus (QFT-Plus) is the new generation of
QuantiFERON-TB Gold In-Tube test to identify latent tuberculosis infection (LTBI). QFT-Plus …

Pediatric tuberculosis management: a global challenge or breakthrough?

LNF Maphalle, BB Michniak-Kohn, MO Ogunrombi… - Children, 2022 - mdpi.com
Managing pediatric tuberculosis (TB) remains a public health problem requiring urgent and
long-lasting solutions as TB is one of the top ten causes of ill health and death in children as …

[HTML][HTML] The effectiveness and cost-effectiveness of screening for latent tuberculosis among migrants in the EU/EEA: a systematic review

C Greenaway, M Pareek, CN Abou Chakra… - …, 2018 - eurosurveillance.org
Background Migrants account for a large and growing proportion of tuberculosis (TB) cases
in low-incidence countries in the European Union/European Economic Area (EU/EEA) …

[HTML][HTML] Analytical evaluation of QuantiFERON-Plus and QuantiFERON-Gold In-tube assays in subjects with or without tuberculosis

E Petruccioli, V Vanini, T Chiacchio, G Cuzzi, DM Cirillo… - Tuberculosis, 2017 - Elsevier
Abstract The QuantiFERON-TB Gold Plus (QFT-Plus) represents the new QuantiFERON-TB
Gold In-tube (QFT-GIT) to identify latent tuberculosis infection (LTBI). The main differences is …

QuantiFERON TB Gold Plus for the diagnosis of tuberculosis: a systematic review and meta-analysis

G Sotgiu, L Saderi, E Petruccioli, S Aliberti, A Piana… - Journal of Infection, 2019 - Elsevier
Estimated 2017 tuberculosis (TB) incidence is 10 million and mainly depends on the
reservoir of individuals with latent TB infection (LTBI). QuantiferonⓇ-TB Gold in-Tube (QFT …

[HTML][HTML] Preventing the spread of multidrug-resistant tuberculosis and protecting contacts of infectious cases

GJ Fox, HS Schaaf, A Mandalakas, E Chiappini… - Clinical Microbiology …, 2017 - Elsevier
Prevention of multidrug-resistant and extensively drug-resistant tuberculosis (MDR/XDR-TB)
is a top priority for global TB control, given the need to limit epidemic spread and …