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Micro/nanosystems for controllable drug delivery to the brain
Drug delivery to the brain is crucial in the treatment for central nervous system disorders.
While significant progress has been made in recent years, there are still major challenges in …
While significant progress has been made in recent years, there are still major challenges in …
Nucleic acid drugs: recent progress and future perspectives
X Sun, S Setrerrahmane, C Li, J Hu, H Xu - Signal Transduction and …, 2024 - nature.com
High efficacy, selectivity and cellular targeting of therapeutic agents has been an active area
of investigation for decades. Currently, most clinically approved therapeutics are small …
of investigation for decades. Currently, most clinically approved therapeutics are small …
Exosomal circRNAs: Novel biomarkers and therapeutic targets for urinary tumors
Q Liu, S Li - Cancer Letters, 2024 - Elsevier
Exosomal circRNAs have emerged as promising biomarkers and therapeutic targets for
urinary tumors. In this review, we explored the intricate role of exosomal circRNAs in …
urinary tumors. In this review, we explored the intricate role of exosomal circRNAs in …
Exosomes as therapeutic and drug delivery vehicle for neurodegenerative diseases
Neurodegenerative disorders are complex, progressive, and life-threatening. They cause
mortality and disability for millions of people worldwide. Appropriate treatment for …
mortality and disability for millions of people worldwide. Appropriate treatment for …
[HTML][HTML] Dendritic cell-derived exosomes in cancer immunotherapy
S Luo, J Chen, F Xu, H Chen, Y Li, W Li - Pharmaceutics, 2023 - mdpi.com
Exosomes are nanoscale vesicles released by diverse types of cells for complex
intercellular communication. Numerous studies have shown that exosomes can regulate the …
intercellular communication. Numerous studies have shown that exosomes can regulate the …
Exosome-based macromolecular neurotherapeutic drug delivery approaches in overcoming the blood-brain barrier for treating brain disorders
Delivering drugs to the brain is a complex challenge in medical research, particularly for
disorders like Alzheimer's and Parkinson's. The blood–brain barrier restricts the entry of …
disorders like Alzheimer's and Parkinson's. The blood–brain barrier restricts the entry of …
Advances in development of exosomes for ophthalmic therapeutics
Y Tian, T Zhang, J Li, Y Tao - Advanced Drug Delivery Reviews, 2023 - Elsevier
Exosomes contain multiple bioactive molecules and maintain the connection between cells.
Recent advances in exosome-based therapeutics have witnessed unprecedented …
Recent advances in exosome-based therapeutics have witnessed unprecedented …
Recent advances in biomimetic strategies for the immunotherapy of glioblastoma
Immunotherapy is regarded as one of the most promising approaches for treating tumors,
with a multitude of immunotherapeutic thoughts currently under consideration for the lethal …
with a multitude of immunotherapeutic thoughts currently under consideration for the lethal …
Therapeutic and diagnostic potential of exosomes as drug delivery systems in brain cancer
DI Avgoulas, KS Tasioulis, RM Papi, AA Pantazaki - Pharmaceutics, 2023 - mdpi.com
Cancer is designated as one of the principal causes of mortality universally. Among different
types of cancer, brain cancer remains the most challenging one due to its aggressiveness …
types of cancer, brain cancer remains the most challenging one due to its aggressiveness …
Peripheral extracellular vesicles in neurodegeneration: pathogenic influencers and therapeutic vehicles
X Liu, L Shen, M Wan, H **e, Z Wang - Journal of Nanobiotechnology, 2024 - Springer
Neurodegenerative diseases (NDDs) such as Alzheimer's disease, Parkinson's disease,
and amyotrophic lateral sclerosis epitomize a class of insidious and relentless neurological …
and amyotrophic lateral sclerosis epitomize a class of insidious and relentless neurological …