SUMO interacting motifs: structure and function
TY Yau, W Sander, C Eidson, AJ Courey - Cells, 2021 - mdpi.com
Small ubiquitin-related modifier (SUMO) is a member of the ubiquitin-related protein family.
SUMO modulates protein function through covalent conjugation to lysine residues in a large …
SUMO modulates protein function through covalent conjugation to lysine residues in a large …
SUMO-SIM interactions: From structure to biological functions
J Lascorz, J Codina-Fabra, D Reverter… - Seminars in Cell & …, 2022 - Elsevier
Post-translational modification by Small Ubiquitin-like Modifier (SUMO) proteins regulates
numerous cellular processes. This modification involves the covalent and reversible …
numerous cellular processes. This modification involves the covalent and reversible …
Paradoxes of cellular SUMOylation regulation: a role of biomolecular condensates?
X Cheng, W Yang, W Lin, F Mei, G Schulte - Pharmacological Reviews, 2023 - Elsevier
Protein SUMOylation is a major post-translational modification essential for maintaining
cellular homeostasis. SUMOylation has long been associated with stress responses as a …
cellular homeostasis. SUMOylation has long been associated with stress responses as a …
SUMOylation-mediated PSME3-20S proteasomal degradation of transcription factor CP2c is crucial for cell cycle progression
SH Son, MY Kim, YS Lim, HC **, JH Shin, JK Yi… - Science …, 2023 - science.org
Transcription factor CP2c (also known as TFCP2, α-CP2, LSF, and LBP-1c) is involved in
diverse ubiquitous and tissue/stage-specific cellular processes and in human malignancies …
diverse ubiquitous and tissue/stage-specific cellular processes and in human malignancies …
Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs
Post-translational modification of proteins by ubiquitin and ubiquitin-like modifiers, such as
SUMO, are key events in protein homeostasis or DNA damage response. Smc5/6 is a …
SUMO, are key events in protein homeostasis or DNA damage response. Smc5/6 is a …
The role of SUMO E3 ligases in signaling pathway of cancer cells
X Shi, Y Du, S Li, H Wu - International journal of molecular sciences, 2022 - mdpi.com
Small ubiquitin-like modifier (SUMO) ylation is a reversible post-translational modification
that plays a crucial role in numerous aspects of cell physiology, including cell cycle …
that plays a crucial role in numerous aspects of cell physiology, including cell cycle …
Zinc controls PML nuclear body formation through regulation of a paralog specific auto-inhibition in SUMO1
M Lussier-Price, HM Wahba, XH Mascle… - Nucleic acids …, 2022 - academic.oup.com
SUMO proteins are important regulators of many key cellular functions in part through their
ability to form interactions with other proteins containing SUMO interacting motifs (SIMs) …
ability to form interactions with other proteins containing SUMO interacting motifs (SIMs) …
Crosstalk between PKA and PIAS3 regulates cardiac Kv4 channel SUMOylation
Post-translational SUMOylation of nuclear and cytosolic proteins maintains homeostasis in
eukaryotic cells and orchestrates programmed responses to changes in metabolic demand …
eukaryotic cells and orchestrates programmed responses to changes in metabolic demand …
Unorthodox PCNA binding by chromatin assembly factor 1
A Gopinathan Nair, N Rabas, S Lejon… - International journal of …, 2022 - mdpi.com
The eukaryotic DNA replication fork is a hub of enzymes that continuously act to synthesize
DNA, propagate DNA methylation and other epigenetic marks, perform quality control, repair …
DNA, propagate DNA methylation and other epigenetic marks, perform quality control, repair …
PIAS1 potentiates the anti-EBV activity of SAMHD1 through SUMOylation
Background Sterile alpha motif and HD domain 1 (SAMHD1) is a deoxynucleotide
triphosphohydrolase (dNTPase) that restricts the infection of a variety of RNA and DNA …
triphosphohydrolase (dNTPase) that restricts the infection of a variety of RNA and DNA …