Recent advances in the synthesis, reaction, and bio-evaluation potential of purines as precursor pharmacophores in chemical reactions: a review

A Ragab - RSC advances, 2025 - pubs.rsc.org
Purines are nitrogenous heterocyclic compounds characterized by the presence of two
fused rings: pyrimidine and imidazole. Their significance is underscored by their widespread …

[HTML][HTML] Targeting senescent cells to reshape the tumor microenvironment and improve anticancer efficacy

B Jiang, W Zhang, X Zhang, Y Sun - Seminars in Cancer Biology, 2024 - Elsevier
Cancer is daunting pathology with remarkable breadth and scope, spanning genetics,
epigenetics, proteomics, metalobomics and cell biology. Cellular senescence represents a …

Design, synthesis, anticancer and in silico assessment of 8-caffeinyl chalcone hybrid conjugates

MNS Rad, S Behrouz, M Charbaghi, M Behrouz… - RSC …, 2024 - pubs.rsc.org
In this paper, we report the design, synthesis, and characterization of novel 8-caffeinyl
chalcone hybrid conjugates, which were studied for their anticancer properties, toxicity, and …

Design, synthesis, analgesic, antibacterial and docking studies of novel 8-piperazinylcaffeine carboxylate ionic liquids

MNS Rad, S Behrouz, PH Yazdi, SS Hashemi… - RSC …, 2024 - pubs.rsc.org
This paper presents a comprehensive evaluation of novel 8-piperazinylcaffeine carboxylate
ionic liquids, including their design, synthesis, characterization, analgesic and antibacterial …