Voltage-dependent L-type Ca2+ channels are multisubunit transmembrane proteins, which
allow the influx of Ca2+ (I Ca) essential for normal excitability and excitation-contraction …

INTRODUCTION: To evaluate the viability of a muscle tissue, it is essential to measure the
tissue's contractile performance as well as to control its structure. Accurate contractility data …

Voltage-dependent Ca 2+ channel (Ca v 1.2, L-type Ca 2+ channel) function is highly
regulated by hormones and neurotransmitters in large part through the activation of kinases …

Cardiac hypertrophy is an adaptive process against increased work loads; however,
hypertrophy also presents substrates for lethal ventricular arrhythmias, resulting in sudden …

Angiotensin II (ANG II) evokes positive inotropic responses in various species. However, the
effects of this peptide on L-type Ca2+ currents (I Ca) are still controversial. We report in this …

Endothelin-1 and photoreleased diacylglycerol increase L-type Ca2+ current by activation of
protein kinase C in rat ventricular myocytes - PMC Back to Top Skip to main content NIH NLM …

Cantu syndrome (CS) is caused by gain-of-function (GOF) mutations in genes encoding
pore-forming (Kir6. 1, KCNJ8) and accessory (SUR2, ABCC9) KATP channel subunits. We …

Studies have suggested that integration of kinase and phosphatase activities maintains the
steady‐state L‐type Ca2+ current in ventricular myocytes, a balance disrupted in failing …

Endothelin-1 (ET-1) is elevated in patients with atrial fibrillation (AF) and heart failure. We
investigated effects of ET-1 on human atrial cellular electrophysiological measurements …

The effects of α 1-adrenoceptor stimulation on intracellular Ca 2+ transients, contractility and
L-type Ca 2+ current (I Ca, L) were studied in single cells isolated from ventricles of guinea …