Stimuli-responsive polysaccharide-based smart hydrogels for diabetic wound healing: Design aspects, preparation methods and regulatory perspectives
Diabetes adversely affects wound-healing responses, leading to the development of chronic
infected wounds. Such wound microenvironment is characterized by hyperglycaemia …
infected wounds. Such wound microenvironment is characterized by hyperglycaemia …
Multi-Functional hydrogels to promote diabetic wound Healing: A review
Y Yang, S Zhong, F Meng, X Cui - Chemical Engineering Journal, 2024 - Elsevier
Hyperglycemia, excess accumulation of ROS, persistent inflammation, hypoxia, macrophage
dysfunction and excessive pro-inflammatory factors could hinder the healing of diabetic …
dysfunction and excessive pro-inflammatory factors could hinder the healing of diabetic …
Diabetic keratopathy: redox signaling pathways and therapeutic prospects
Diabetes mellitus, the most prevalent endocrine disorder, not only impacts the retina but also
significantly involves the ocular surface. Diabetes contributes to the development of dry eye …
significantly involves the ocular surface. Diabetes contributes to the development of dry eye …
[HTML][HTML] A review: Polysaccharides targeting mitochondria to improve obesity
Y Chen, R Gao, J Fang, S Ding - International Journal of Biological …, 2024 - Elsevier
Polysaccharides are one of the most important and widely used bioactive components of
natural products, which can be used to treat metabolic diseases. Natural polysaccharides …
natural products, which can be used to treat metabolic diseases. Natural polysaccharides …
[HTML][HTML] Discussing pathologic mechanisms of Diabetic retinopathy & therapeutic potentials of curcumin and β-glucogallin in the management of Diabetic retinopathy
Diabetic retinopathy (DR) is a form of retinal microangiopathy that occurs as a result of long-
term Diabetes mellitus (DM). Patients with Diabetes mellitus typically suffer from DR as a …
term Diabetes mellitus (DM). Patients with Diabetes mellitus typically suffer from DR as a …
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
Systemic aging influences various physiological processes and contributes to structural and
functional decline in cardiac tissue. These alterations include an increased incidence of left …
functional decline in cardiac tissue. These alterations include an increased incidence of left …
[HTML][HTML] Pharmacotherapeutic considerations on telomere biology: The positive effect of pharmacologically active substances on telomere length
Telomeres are part of chromatin structures containing repeated DNA sequences, which
function as protective caps at the ends of chromosomes and prevent DNA degradation and …
function as protective caps at the ends of chromosomes and prevent DNA degradation and …
Therapeutic effects of mesenchymal stromal cells require mitochondrial transfer and quality control
Due to their beneficial effects in an array of diseases, Mesenchymal Stromal Cells (MSCs)
have been the focus of intense preclinical research and clinical implementation for decades …
have been the focus of intense preclinical research and clinical implementation for decades …
The anti-diabetic potential of baicalin: evidence from rodent studies
Baicalin is a biologically active flavonoid compound that benefits the organism in various
pathological conditions. Rodent studies have shown that this compound effectively …
pathological conditions. Rodent studies have shown that this compound effectively …
[HTML][HTML] Insulin oxidation and oxidative modifications alter glucose uptake, cell metabolism, and inflammatory secretion profiles
R Clemen, W Dethloff, J Berner, P Schulan, A Martinet… - Redox biology, 2024 - Elsevier
Insulin participates in glucose homeostasis in the body and regulates glucose, protein, and
lipid metabolism. Chronic hyperglycemia triggers oxidative stress and the generation of …
lipid metabolism. Chronic hyperglycemia triggers oxidative stress and the generation of …