The UBXD family is a diverse group of UBX (ubiquitin-regulatory X) domain-containing
proteins in mammalian cells. Members of this family contain a UBX domain typically located …

To make full use both of optical properties of quantum dots (QDs) and of specific interactions
between aptamers and their ligands of interest, we employed QD-conjugated RNA aptamer …

p97/VCP is a hexameric ATPase that is coupled to diverse cellular processes, such as
membrane fusion and proteolysis. How p97 activity is regulated is not fully understood. Here …

UBXD family (UBXDF), a group of proteins containing ubiquitin regulatory X (UBX) domains,
play a crucial role in the imbalance of proliferation and apoptotic in cancer. In this study, we …

The UBX domain of Fas-associated factor 1 (FAF1) binds to the N domain of p97/VCP, a
multi-functional hexameric ATPase, and FAF1 thus inhibits the proteasome-mediated protein …

Fas-associated factor 1 (FAF1) is a multifunctional pro-apoptotic protein that is involved in
Fas-mediated apoptosis, NF-κB signalling and the ubiquitin–proteasome pathway. In the …

Introduction: Cdc48 of S. cerevisiae (homologue of p97/VCP in mammals) is a highly
conserved, abundant and essential AAA-ATPase. It assembles in a homo-hexamer structure …

This study focuses on the functional aspects of Cdc48, an intriguing molecular machine. The
Cdc48 complex is a member of the AAA+(ATPases associated with diverse cellular …

UBX domain-containing proteins act as co-factors for the AAA+ ATPase p97, and specify a
wide variety of cellular functions. These include membrane extraction of proteins destined …

INTRODUCTION p97/valosin-containing protein (VCP) is an ATPase of the AAA1 family and
has been implicated in diverse cellular processes: post-mitotic Golgi reassembly …