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[HTML][HTML] Sex chromosome specialization and degeneration in mammals
JAM Graves - Cell, 2006 - cell.com
Sex chromosomes—particularly the human Y—have been a source of fascination for
decades because of their unique transmission patterns and their peculiar cytology. The …
decades because of their unique transmission patterns and their peculiar cytology. The …
Evolution of vertebrate sex chromosomes and dosage compensation
JAM Graves - Nature Reviews Genetics, 2016 - nature.com
Differentiated sex chromosomes in mammals and other vertebrates evolved independently
but in strikingly similar ways. Vertebrates with differentiated sex chromosomes share the …
but in strikingly similar ways. Vertebrates with differentiated sex chromosomes share the …
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
Although iron is required to sustain life, its free concentration and metabolism have to be
tightly regulated. This is achieved through a variety of iron-binding proteins including …
tightly regulated. This is achieved through a variety of iron-binding proteins including …
The avian Z-linked gene DMRT1 is required for male sex determination in the chicken
CA Smith, KN Roeszler, T Ohnesorg, DM Cummins… - Nature, 2009 - nature.com
Sex in birds is chromosomally based, as in mammals, but the sex chromosomes are different
and the mechanism of avian sex determination has been a long-standing mystery,,. In the …
and the mechanism of avian sex determination has been a long-standing mystery,,. In the …
Primary sex determination in birds depends on DMRT1 dosage, but gonadal sex does not determine adult secondary sex characteristics
J Ioannidis, G Taylor, D Zhao, L Liu… - Proceedings of the …, 2021 - pnas.org
In birds, males are the homogametic sex (ZZ) and females the heterogametic sex (ZW).
Primary sex determination is thought to depend on a sex chromosome gene dosage …
Primary sex determination is thought to depend on a sex chromosome gene dosage …
Genome editing reveals dmrt1 as an essential male sex-determining gene in Chinese tongue sole (Cynoglossus semilaevis)
Chinese tongue sole is a marine fish with ZW sex determination. Genome sequencing
suggested that the Z-linked dmrt1 is a putative male determination gene, but direct genetic …
suggested that the Z-linked dmrt1 is a putative male determination gene, but direct genetic …
A duplicated copy of DMRT1 in the sex-determining region of the Y chromosome of the medaka, Oryzias latipes
I Nanda, M Kondo, U Hornung, S Asakawa… - Proceedings of the …, 2002 - pnas.org
The genes that determine the development of the male or female sex are known in
Caenorhabditis elegans, Drosophila, and most mammals. In many other organisms the …
Caenorhabditis elegans, Drosophila, and most mammals. In many other organisms the …
Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation
CS Raymond, MW Murphy, MG O'Sullivan… - Genes & …, 2000 - genesdev.cshlp.org
The only molecular similarity in sex determination found so far among phyla is between the
Drosophila doublesex (dsx) and Caenorhabditis elegans mab-3 genes. dsx and mab-3 …
Drosophila doublesex (dsx) and Caenorhabditis elegans mab-3 genes. dsx and mab-3 …
Zebrafish comparative genomics and the origins of vertebrate chromosomes
JH Postlethwait, IG Woods, P Ngo-Hazelett… - Genome …, 2000 - genome.cshlp.org
To help understand mechanisms of vertebrate genome evolution, we have compared
zebrafish and tetrapod gene maps. It has been suggested that translocations are fixed more …
zebrafish and tetrapod gene maps. It has been suggested that translocations are fixed more …
A W-linked DM-domain gene, DM-W, participates in primary ovary development in Xenopus laevis
S Yoshimoto, E Okada, H Umemoto, K Tamura… - Proceedings of the …, 2008 - pnas.org
In the XX/XY sex-determining system, the Y-linked SRY genes of most mammals and the
DMY/Dmrt1bY genes of the teleost fish medaka have been characterized as sex …
DMY/Dmrt1bY genes of the teleost fish medaka have been characterized as sex …