Diagnosis and management of autoimmune hepatitis

L Muratori, AW Lohse, M Lenzi - bmj, 2023 - bmj.com
Autoimmune hepatitis is an inflammatory disease of the liver of unknown cause that may
progress to liver cirrhosis and end stage liver failure if diagnosis is overlooked and treatment …

Global incidence and prevalence of autoimmune hepatitis, 1970–2022: a systematic review and meta-analysis

JW Hahn, HR Yang, JS Moon, JY Chang, K Lee… - …, 2023 - thelancet.com
Background Autoimmune hepatitis (AIH) varies significantly in incidence and prevalence
across countries and regions. We aimed to examine global, regional, and national trends in …

Non-alcoholic fatty liver disease and gut microbial dysbiosis-underlying mechanisms and gut microbiota mediated treatment strategies

M Jayachandran, S Qu - Reviews in Endocrine and Metabolic Disorders, 2023 - Springer
Non-alcoholic fatty liver disease (NAFLD) is by far the most prevalent form of liver disease
worldwide. It's also the leading cause of liver-related hospitalizations and deaths …

Research gaps and opportunities in autoimmune hepatitis—Results of the international autoimmune hepatitis group research workshop 2022

RJ Snijders, DN Assis, YH Oo, M Sebode… - Liver …, 2023 - Wiley Online Library
Autoimmune hepatitis (AIH) is a rare autoimmune liver disease that is characterised by a
chronic inflammatory immune reaction directed against hepatocytes. The disease results in …

Role of the gut–liver axis in the pathobiology of cholangiopathies: Basic and clinical evidence

MC Bragazzi, R Venere, A Vignone, D Alvaro… - International Journal of …, 2023 - mdpi.com
The “Gut–Liver Axis” refers to the physiological bidirectional interplay between the gut and
its microbiota and the liver which, in health, occurs thanks to a condition of immune …

Clinicopathologic features of severe acute hepatitis associated with adenovirus infection in children

J Liang, DR Kelly, A Pai, LA Gillis… - The American Journal …, 2023 - journals.lww.com
A recent increase in reports of severe acute hepatitis of unknown etiology in children is
under investigation. Although adenovirus has been frequently detected, its role remains …

Role of microbiome in autoimmune liver diseases

KM Schneider, M Kummen, PJ Trivedi, JR Hov - Hepatology, 2024 - journals.lww.com
The microbiome plays a crucial role in integrating environmental influences into host
physiology, potentially linking it to autoimmune liver diseases, such as autoimmune …

[HTML][HTML] Advances in understanding and managing autoimmune hepatitis: a narrative review

V Yadav, R Irfan, S Safdar, V Sunkara, C Ekhator… - Cureus, 2023 - ncbi.nlm.nih.gov
Autoimmune hepatitis (AIH) is a chronic liver disease characterized by immune-mediated
destruction of hepatocytes, leading to inflammation and fibrosis. In recent years, significant …

Inflammasome and pyroptosis in autoimmune liver diseases

J Wang, Z Sun, J **e, W Ji, Y Cui, Z Ai… - Frontiers in …, 2023 - frontiersin.org
Autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), primary sclerosing cholangitis
(PSC), and IgG4-related sclerosing cholangitis (IgG4-SC) are the four main forms of …

Incorporating the molecular mimicry of environmental antigens into the causality of autoimmune hepatitis

AJ Czaja - Digestive Diseases and Sciences, 2023 - Springer
Molecular mimicry between foreign and self-antigens has been implicated as a cause of
autoimmune hepatitis in experimental models and cross-reacting antibodies in patients. This …