Chikungunya: a potentially emerging epidemic?

MM Thiboutot, S Kannan, OU Kawalekar… - PLoS neglected …, 2010 - journals.plos.org
Chikungunya virus is a mosquito-borne emerging pathogen that has a major health impact
in humans and causes fever disease, headache, rash, nausea, vomiting, myalgia, and …

Chikungunya virus infection

F Simon, E Javelle, M Oliver, I Leparc-Goffart… - Current infectious …, 2011 - Springer
Chikungunya virus (CHIKV) is an alphavirus transmitted by mosquitoes, mostly Aedes
aegypti and Aedes albopictus. After half a century of focal outbreaks of acute febrile …

Genome-scale phylogenetic analyses of chikungunya virus reveal independent emergences of recent epidemics and various evolutionary rates

SM Volk, R Chen, KA Tsetsarkin, AP Adams… - Journal of …, 2010 - Am Soc Microbiol
Chikungunya virus (CHIKV), a mosquito-borne alphavirus, has traditionally circulated in
Africa and Asia, causing human febrile illness accompanied by severe, chronic joint pain. In …

Chikungunya fever: a clinical and virological investigation of outpatients on Reunion Island, South-West Indian Ocean

SD Thiberville, V Boisson, J Gaudart… - PLoS neglected …, 2013 - journals.plos.org
Background Chikungunya virus (CHIKV) is responsible for acute febrile polyarthralgia and,
in a proportion of cases, severe complications including chronic arthritis. CHIKV has spread …

Current status of dengue and chikungunya in India

D Cecilia - WHO South-East Asia journal of public health, 2014 - journals.lww.com
Dengue, a Flavivirus and chikungunya, an Alphavirus, transmitted by Aedes mosquitoes, are
a cause of great concern to public health in India. Every year, thousands of individuals are …

Activity of andrographolide against chikungunya virus infection

P Wintachai, P Kaur, RCH Lee, S Ramphan… - Scientific reports, 2015 - nature.com
Chikungunya virus (CHIKV) is a re-emerging mosquito-borne alphavirus that has recently
engendered large epidemics around the world. There is no specific antiviral for treatment of …

Assessment of in vitro prophylactic and therapeutic efficacy of chloroquine against Chikungunya virus in vero cells

M Khan, SR Santhosh, M Tiwari… - Journal of medical …, 2010 - Wiley Online Library
The resurgence of Chikungunya virus (CHIKV) in the form of unprecedented and explosive
epidemics in India and the Indian Ocean islands after a gap of 32 years is a major public …

Identification of prohibitin as a Chikungunya virus receptor protein

P Wintachai, N Wikan, A Kuadkitkan… - Journal of medical …, 2012 - Wiley Online Library
Chikungunya virus (CHIKV) has recently re‐emerged causing millions of infections in
countries around the Indian Ocean. While CHIKV has a broad host cell range and …

Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization

S Sun, Y **ang, W Akahata, H Holdaway, P Pal… - Elife, 2013 - elifesciences.org
A 5.3 Å resolution, cryo-electron microscopy (cryoEM) map of Chikungunya virus-like
particles (VLPs) has been interpreted using the previously published crystal structure of the …

A DNA vaccine against chikungunya virus is protective in mice and induces neutralizing antibodies in mice and nonhuman primates

K Mallilankaraman, DJ Shedlock, H Bao… - PLoS neglected …, 2011 - journals.plos.org
Chikungunya virus (CHIKV) is an emerging mosquito-borne alphavirus indigenous to
tropical Africa and Asia. Acute illness is characterized by fever, arthralgias, conjunctivitis …